Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center

Solonirina Davida Rakotomena; Sedera Arimino; Medyno Mampiadana Lovasoa; Tianarivelo Rajaonarivony; Hery Nirina Rakoto Ratsimba

doi:doi:10.11648/j.sjcm.20190806.12

Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center

Solonirina Davida Rakotomena, Sedera Arimino, Medyno Mampiadana Lovasoa, Tianarivelo Rajaonarivony, Hery Nirina Rakoto Ratsimba

Published in Science Journal of Clinical Medicine (Volume 8, Issue 6)

Received: 4 December 2019 Accepted: 20 December 2019 Published: 4 January 2020

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Abstract

Despite the introduction of H2 receptor and proton pump antagonists into the therapeutic arsenal of the Peptic Ulcer Disease, gastric perforation remains the most common surgical emergery for the upper gastrointestinal tract. The present study aims to describe the particularities of the management of Perforated Peptic Ulcer which underwent surgery in the University Hospital Center Joseph Ravoahangy Andrianavalona Antananarivo (CHU-JRA) and to identify its morbidity and mortality factors. This is a retrospective analysis performed over a period of 33 months from January 2017 to September 2019 on Perforated Peptic Ulcer operated in CHU-JRA. Demographic, clinical and therapeutic parameters were studied and analyzed in relation to the morbidity and mortality rate. Altogether 158 patients operated for perforated Gastric or Duodenal Ulcer were included with an age ranging from 16 to 78 years old, a mean age of 39.05±15.03 years and a Sex Ratio estimated to 18.75. Repeated unexplored epigastralgia was noted in 70.89% of cases and 33.54% of patients used NSAIDs and/or corticosteroids before the onset of the pain. At admission, 9.4% of cases were immediately in shock. A laparotomy for exploration and repair was performed for a suspicion of a hollow-organ perforation on a X-ray of an Unprepared Abdomen. Antral perforation predominated in our serie (75.95%) and the main repair procedure consisted in a simple surgical suture. To conclude, our stude reflects the difficulty of the management of Peptic Ulcer Disease and its complications in our daily practice. Strenghtening the awareness of the population about the potiential severity of this disease is essential.

Published in	Science Journal of Clinical Medicine (Volume 8, Issue 6)
DOI	10.11648/j.sjcm.20190806.12
Page(s)	66-71
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Helicobacter pylori, Peptic Ulcer Disease, Perforation, Peritonitis, Surgery

References

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APA Style

Solonirina Davida Rakotomena, Sedera Arimino, Medyno Mampiadana Lovasoa, Tianarivelo Rajaonarivony, Hery Nirina Rakoto Ratsimba. (2020). Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center. Science Journal of Clinical Medicine, 8(6), 66-71. https://doi.org/10.11648/j.sjcm.20190806.12

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ACS Style

Solonirina Davida Rakotomena; Sedera Arimino; Medyno Mampiadana Lovasoa; Tianarivelo Rajaonarivony; Hery Nirina Rakoto Ratsimba. Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center. Sci. J. Clin. Med. 2020, 8(6), 66-71. doi: 10.11648/j.sjcm.20190806.12

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AMA Style

Solonirina Davida Rakotomena, Sedera Arimino, Medyno Mampiadana Lovasoa, Tianarivelo Rajaonarivony, Hery Nirina Rakoto Ratsimba. Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center. Sci J Clin Med. 2020;8(6):66-71. doi: 10.11648/j.sjcm.20190806.12

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@article{10.11648/j.sjcm.20190806.12,
  author = {Solonirina Davida Rakotomena and Sedera Arimino and Medyno Mampiadana Lovasoa and Tianarivelo Rajaonarivony and Hery Nirina Rakoto Ratsimba},
  title = {Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center},
  journal = {Science Journal of Clinical Medicine},
  volume = {8},
  number = {6},
  pages = {66-71},
  doi = {10.11648/j.sjcm.20190806.12},
  url = {https://doi.org/10.11648/j.sjcm.20190806.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20190806.12},
  abstract = {Despite the introduction of H2 receptor and proton pump antagonists into the therapeutic arsenal of the Peptic Ulcer Disease, gastric perforation remains the most common surgical emergery for the upper gastrointestinal tract. The present study aims to describe the particularities of the management of Perforated Peptic Ulcer which underwent surgery in the University Hospital Center Joseph Ravoahangy Andrianavalona Antananarivo (CHU-JRA) and to identify its morbidity and mortality factors. This is a retrospective analysis performed over a period of 33 months from January 2017 to September 2019 on Perforated Peptic Ulcer operated in CHU-JRA. Demographic, clinical and therapeutic parameters were studied and analyzed in relation to the morbidity and mortality rate. Altogether 158 patients operated for perforated Gastric or Duodenal Ulcer were included with an age ranging from 16 to 78 years old, a mean age of 39.05±15.03 years and a Sex Ratio estimated to 18.75. Repeated unexplored epigastralgia was noted in 70.89% of cases and 33.54% of patients used NSAIDs and/or corticosteroids before the onset of the pain. At admission, 9.4% of cases were immediately in shock. A laparotomy for exploration and repair was performed for a suspicion of a hollow-organ perforation on a X-ray of an Unprepared Abdomen. Antral perforation predominated in our serie (75.95%) and the main repair procedure consisted in a simple surgical suture. To conclude, our stude reflects the difficulty of the management of Peptic Ulcer Disease and its complications in our daily practice. Strenghtening the awareness of the population about the potiential severity of this disease is essential.},
 year = {2020}
}

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TY  - JOUR
T1  - Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center
AU  - Solonirina Davida Rakotomena
AU  - Sedera Arimino
AU  - Medyno Mampiadana Lovasoa
AU  - Tianarivelo Rajaonarivony
AU  - Hery Nirina Rakoto Ratsimba
Y1  - 2020/01/04
PY  - 2020
N1  - https://doi.org/10.11648/j.sjcm.20190806.12
DO  - 10.11648/j.sjcm.20190806.12
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 66
EP  - 71
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20190806.12
AB  - Despite the introduction of H2 receptor and proton pump antagonists into the therapeutic arsenal of the Peptic Ulcer Disease, gastric perforation remains the most common surgical emergery for the upper gastrointestinal tract. The present study aims to describe the particularities of the management of Perforated Peptic Ulcer which underwent surgery in the University Hospital Center Joseph Ravoahangy Andrianavalona Antananarivo (CHU-JRA) and to identify its morbidity and mortality factors. This is a retrospective analysis performed over a period of 33 months from January 2017 to September 2019 on Perforated Peptic Ulcer operated in CHU-JRA. Demographic, clinical and therapeutic parameters were studied and analyzed in relation to the morbidity and mortality rate. Altogether 158 patients operated for perforated Gastric or Duodenal Ulcer were included with an age ranging from 16 to 78 years old, a mean age of 39.05±15.03 years and a Sex Ratio estimated to 18.75. Repeated unexplored epigastralgia was noted in 70.89% of cases and 33.54% of patients used NSAIDs and/or corticosteroids before the onset of the pain. At admission, 9.4% of cases were immediately in shock. A laparotomy for exploration and repair was performed for a suspicion of a hollow-organ perforation on a X-ray of an Unprepared Abdomen. Antral perforation predominated in our serie (75.95%) and the main repair procedure consisted in a simple surgical suture. To conclude, our stude reflects the difficulty of the management of Peptic Ulcer Disease and its complications in our daily practice. Strenghtening the awareness of the population about the potiential severity of this disease is essential.
VL  - 8
IS  - 6
ER  -

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Author Information

Solonirina Davida Rakotomena

Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Sedera Arimino

Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Medyno Mampiadana Lovasoa

Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Tianarivelo Rajaonarivony

Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar
Hery Nirina Rakoto Ratsimba

Faculty of Medicine, University of Antananarivo, Antananarivo, Madagascar

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APA Style

Solonirina Davida Rakotomena, Sedera Arimino, Medyno Mampiadana Lovasoa, Tianarivelo Rajaonarivony, Hery Nirina Rakoto Ratsimba. (2020). Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center. Science Journal of Clinical Medicine, 8(6), 66-71. https://doi.org/10.11648/j.sjcm.20190806.12

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ACS Style

Solonirina Davida Rakotomena; Sedera Arimino; Medyno Mampiadana Lovasoa; Tianarivelo Rajaonarivony; Hery Nirina Rakoto Ratsimba. Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center. Sci. J. Clin. Med. 2020, 8(6), 66-71. doi: 10.11648/j.sjcm.20190806.12

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AMA Style

Solonirina Davida Rakotomena, Sedera Arimino, Medyno Mampiadana Lovasoa, Tianarivelo Rajaonarivony, Hery Nirina Rakoto Ratsimba. Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center. Sci J Clin Med. 2020;8(6):66-71. doi: 10.11648/j.sjcm.20190806.12

Copy | Download

@article{10.11648/j.sjcm.20190806.12,
  author = {Solonirina Davida Rakotomena and Sedera Arimino and Medyno Mampiadana Lovasoa and Tianarivelo Rajaonarivony and Hery Nirina Rakoto Ratsimba},
  title = {Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center},
  journal = {Science Journal of Clinical Medicine},
  volume = {8},
  number = {6},
  pages = {66-71},
  doi = {10.11648/j.sjcm.20190806.12},
  url = {https://doi.org/10.11648/j.sjcm.20190806.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20190806.12},
  abstract = {Despite the introduction of H2 receptor and proton pump antagonists into the therapeutic arsenal of the Peptic Ulcer Disease, gastric perforation remains the most common surgical emergery for the upper gastrointestinal tract. The present study aims to describe the particularities of the management of Perforated Peptic Ulcer which underwent surgery in the University Hospital Center Joseph Ravoahangy Andrianavalona Antananarivo (CHU-JRA) and to identify its morbidity and mortality factors. This is a retrospective analysis performed over a period of 33 months from January 2017 to September 2019 on Perforated Peptic Ulcer operated in CHU-JRA. Demographic, clinical and therapeutic parameters were studied and analyzed in relation to the morbidity and mortality rate. Altogether 158 patients operated for perforated Gastric or Duodenal Ulcer were included with an age ranging from 16 to 78 years old, a mean age of 39.05±15.03 years and a Sex Ratio estimated to 18.75. Repeated unexplored epigastralgia was noted in 70.89% of cases and 33.54% of patients used NSAIDs and/or corticosteroids before the onset of the pain. At admission, 9.4% of cases were immediately in shock. A laparotomy for exploration and repair was performed for a suspicion of a hollow-organ perforation on a X-ray of an Unprepared Abdomen. Antral perforation predominated in our serie (75.95%) and the main repair procedure consisted in a simple surgical suture. To conclude, our stude reflects the difficulty of the management of Peptic Ulcer Disease and its complications in our daily practice. Strenghtening the awareness of the population about the potiential severity of this disease is essential.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Clinical and Therapeutic Aspects of Perforated Peptic Ulcer in Joseph Ravoahangy Andrianavalona University Hospital Center
AU  - Solonirina Davida Rakotomena
AU  - Sedera Arimino
AU  - Medyno Mampiadana Lovasoa
AU  - Tianarivelo Rajaonarivony
AU  - Hery Nirina Rakoto Ratsimba
Y1  - 2020/01/04
PY  - 2020
N1  - https://doi.org/10.11648/j.sjcm.20190806.12
DO  - 10.11648/j.sjcm.20190806.12
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 66
EP  - 71
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20190806.12
AB  - Despite the introduction of H2 receptor and proton pump antagonists into the therapeutic arsenal of the Peptic Ulcer Disease, gastric perforation remains the most common surgical emergery for the upper gastrointestinal tract. The present study aims to describe the particularities of the management of Perforated Peptic Ulcer which underwent surgery in the University Hospital Center Joseph Ravoahangy Andrianavalona Antananarivo (CHU-JRA) and to identify its morbidity and mortality factors. This is a retrospective analysis performed over a period of 33 months from January 2017 to September 2019 on Perforated Peptic Ulcer operated in CHU-JRA. Demographic, clinical and therapeutic parameters were studied and analyzed in relation to the morbidity and mortality rate. Altogether 158 patients operated for perforated Gastric or Duodenal Ulcer were included with an age ranging from 16 to 78 years old, a mean age of 39.05±15.03 years and a Sex Ratio estimated to 18.75. Repeated unexplored epigastralgia was noted in 70.89% of cases and 33.54% of patients used NSAIDs and/or corticosteroids before the onset of the pain. At admission, 9.4% of cases were immediately in shock. A laparotomy for exploration and repair was performed for a suspicion of a hollow-organ perforation on a X-ray of an Unprepared Abdomen. Antral perforation predominated in our serie (75.95%) and the main repair procedure consisted in a simple surgical suture. To conclude, our stude reflects the difficulty of the management of Peptic Ulcer Disease and its complications in our daily practice. Strenghtening the awareness of the population about the potiential severity of this disease is essential.
VL  - 8
IS  - 6
ER  -

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