Celiac disease is an autoimmune enteropathy, secondary to an allergy to gluten in genetically predisposed subjects, results in clinical polymorphism, with the presence of malabsorption syndrome, is a villous atrophy demonstrated using gastroscopy, which allows to biopsy the duodenal mucosa in order to demonstrate this atrophy at the histological level and also the demonstration of basal lymphocytosis, its associated clinical, endoscopic and histological abnormalities are positive for anti- ACs. IgA-type transglutaminase, the latter may be deficient, the chosen which is frequent in celiac patients compared to the general population, making sometimes the diagnosis is a challenge for the clinician. We report the case of an association between an IgA deficiency and celiac disease in a 20-year-old patient with no personal or family pathological history, revealed by diarrhea with signs of deficiency in connection with malabsorption and the presence of the sign suggestive at endoscopy. digestive system, with an analysis of the relationship between seronegative celiac disease (SNCD) and immunoglobulin A deficiency through a review of the literature on the main medical databases
Published in | International Journal of Immunology (Volume 9, Issue 1) |
DOI | 10.11648/j.iji.20210901.13 |
Page(s) | 13-15 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2021. Published by Science Publishing Group |
Celiac Disease, Selective IgA Deficiency, Diagnostic Trap, IgA-tTG, Intestinal Biopsy, Gastroscopy
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APA Style
Hajar Saffour, Hassan Ouaya, Raihane Bahri, Fadoua Elfarssani, Karima Benjouad, et al. (2021). The Association of IgA Deficiency and Celiac Disease: What Hides Under the Iceberg. International Journal of Immunology, 9(1), 13-15. https://doi.org/10.11648/j.iji.20210901.13
ACS Style
Hajar Saffour; Hassan Ouaya; Raihane Bahri; Fadoua Elfarssani; Karima Benjouad, et al. The Association of IgA Deficiency and Celiac Disease: What Hides Under the Iceberg. Int. J. Immunol. 2021, 9(1), 13-15. doi: 10.11648/j.iji.20210901.13
AMA Style
Hajar Saffour, Hassan Ouaya, Raihane Bahri, Fadoua Elfarssani, Karima Benjouad, et al. The Association of IgA Deficiency and Celiac Disease: What Hides Under the Iceberg. Int J Immunol. 2021;9(1):13-15. doi: 10.11648/j.iji.20210901.13
@article{10.11648/j.iji.20210901.13, author = {Hajar Saffour and Hassan Ouaya and Raihane Bahri and Fadoua Elfarssani and Karima Benjouad and Adil Aiterrami and Soufia Oubaha and Zouhour Samlani and Khadija Krati and Brahim Admou}, title = {The Association of IgA Deficiency and Celiac Disease: What Hides Under the Iceberg}, journal = {International Journal of Immunology}, volume = {9}, number = {1}, pages = {13-15}, doi = {10.11648/j.iji.20210901.13}, url = {https://doi.org/10.11648/j.iji.20210901.13}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20210901.13}, abstract = {Celiac disease is an autoimmune enteropathy, secondary to an allergy to gluten in genetically predisposed subjects, results in clinical polymorphism, with the presence of malabsorption syndrome, is a villous atrophy demonstrated using gastroscopy, which allows to biopsy the duodenal mucosa in order to demonstrate this atrophy at the histological level and also the demonstration of basal lymphocytosis, its associated clinical, endoscopic and histological abnormalities are positive for anti- ACs. IgA-type transglutaminase, the latter may be deficient, the chosen which is frequent in celiac patients compared to the general population, making sometimes the diagnosis is a challenge for the clinician. We report the case of an association between an IgA deficiency and celiac disease in a 20-year-old patient with no personal or family pathological history, revealed by diarrhea with signs of deficiency in connection with malabsorption and the presence of the sign suggestive at endoscopy. digestive system, with an analysis of the relationship between seronegative celiac disease (SNCD) and immunoglobulin A deficiency through a review of the literature on the main medical databases}, year = {2021} }
TY - JOUR T1 - The Association of IgA Deficiency and Celiac Disease: What Hides Under the Iceberg AU - Hajar Saffour AU - Hassan Ouaya AU - Raihane Bahri AU - Fadoua Elfarssani AU - Karima Benjouad AU - Adil Aiterrami AU - Soufia Oubaha AU - Zouhour Samlani AU - Khadija Krati AU - Brahim Admou Y1 - 2021/03/03 PY - 2021 N1 - https://doi.org/10.11648/j.iji.20210901.13 DO - 10.11648/j.iji.20210901.13 T2 - International Journal of Immunology JF - International Journal of Immunology JO - International Journal of Immunology SP - 13 EP - 15 PB - Science Publishing Group SN - 2329-1753 UR - https://doi.org/10.11648/j.iji.20210901.13 AB - Celiac disease is an autoimmune enteropathy, secondary to an allergy to gluten in genetically predisposed subjects, results in clinical polymorphism, with the presence of malabsorption syndrome, is a villous atrophy demonstrated using gastroscopy, which allows to biopsy the duodenal mucosa in order to demonstrate this atrophy at the histological level and also the demonstration of basal lymphocytosis, its associated clinical, endoscopic and histological abnormalities are positive for anti- ACs. IgA-type transglutaminase, the latter may be deficient, the chosen which is frequent in celiac patients compared to the general population, making sometimes the diagnosis is a challenge for the clinician. We report the case of an association between an IgA deficiency and celiac disease in a 20-year-old patient with no personal or family pathological history, revealed by diarrhea with signs of deficiency in connection with malabsorption and the presence of the sign suggestive at endoscopy. digestive system, with an analysis of the relationship between seronegative celiac disease (SNCD) and immunoglobulin A deficiency through a review of the literature on the main medical databases VL - 9 IS - 1 ER -