In order to provide new lead compounds of drugs and other useful products, the diversity and some bioactivities of cultivable actinobacteria in bird feces were studied．Six species of bird fecal samples were collected from Yunnan Wild Animal Park and bank of Dian Lake. The pure cultures of actinobacteria were isolated from these samples by using 6 different media. The partial 16S rRNA gene sequences of 207 selected strains were determined, the phylogenetic analysis was carried out, and antimicrobial activities were determined by using agar diffusion method. The key biosynthase genes (CYP, AHBA and SAL) of antibiotics were also detected. Total 28 genera of actinobacteria from all the samples were identified. 18 genera were identified from Pavo cristatus feces, and the actinomycete community was the most complex. These actinobacteria had wide inhibition against 10 test microbes. In 30, 25, and 36 strains of actinobacteria isolated from Pavo cristatus, Grus japonensis and Larus ridibundus feces respectively, average 22.2%, 8.9% and 40.8% strains had the key biosynthase genes encoding CYP, AHBA and SAL. More than 30 bioactive secondary metabolites from several actinomycete strains of bird feces were isolated and characterized. The study shows that birds fecal actinobacteria are a new potential source for discovering new drugs and other industry products.
| Published in | American Journal of BioScience (Volume 2, Issue 1) |
| DOI | 10.11648/j.ajbio.20140201.13 |
| Page(s) | 13-18 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Bird feces, Actinobacteria, Diversity, Bioactivity
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APA Style
Xiu Chen, Shumei Qiu, Yi Jiang, Li Han, Xueshi Huang, et al. (2013). Diversity, Bioactivity and Drug Development of Cultivable Actinobacteria in Six Species of Bird Feces. American Journal of BioScience, 2(1), 13-18. https://doi.org/10.11648/j.ajbio.20140201.13
ACS Style
Xiu Chen; Shumei Qiu; Yi Jiang; Li Han; Xueshi Huang, et al. Diversity, Bioactivity and Drug Development of Cultivable Actinobacteria in Six Species of Bird Feces. Am. J. BioScience 2013, 2(1), 13-18. doi: 10.11648/j.ajbio.20140201.13
AMA Style
Xiu Chen, Shumei Qiu, Yi Jiang, Li Han, Xueshi Huang, et al. Diversity, Bioactivity and Drug Development of Cultivable Actinobacteria in Six Species of Bird Feces. Am J BioScience. 2013;2(1):13-18. doi: 10.11648/j.ajbio.20140201.13
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Download@article{10.11648/j.ajbio.20140201.13,
author = {Xiu Chen and Shumei Qiu and Yi Jiang and Li Han and Xueshi Huang and Chenglin Jiang},
title = {Diversity, Bioactivity and Drug Development of Cultivable Actinobacteria in Six Species of Bird Feces},
journal = {American Journal of BioScience},
volume = {2},
number = {1},
pages = {13-18},
doi = {10.11648/j.ajbio.20140201.13},
url = {https://doi.org/10.11648/j.ajbio.20140201.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20140201.13},
abstract = {In order to provide new lead compounds of drugs and other useful products, the diversity and some bioactivities of cultivable actinobacteria in bird feces were studied．Six species of bird fecal samples were collected from Yunnan Wild Animal Park and bank of Dian Lake. The pure cultures of actinobacteria were isolated from these samples by using 6 different media. The partial 16S rRNA gene sequences of 207 selected strains were determined, the phylogenetic analysis was carried out, and antimicrobial activities were determined by using agar diffusion method. The key biosynthase genes (CYP, AHBA and SAL) of antibiotics were also detected. Total 28 genera of actinobacteria from all the samples were identified. 18 genera were identified from Pavo cristatus feces, and the actinomycete community was the most complex. These actinobacteria had wide inhibition against 10 test microbes. In 30, 25, and 36 strains of actinobacteria isolated from Pavo cristatus, Grus japonensis and Larus ridibundus feces respectively, average 22.2%, 8.9% and 40.8% strains had the key biosynthase genes encoding CYP, AHBA and SAL. More than 30 bioactive secondary metabolites from several actinomycete strains of bird feces were isolated and characterized. The study shows that birds fecal actinobacteria are a new potential source for discovering new drugs and other industry products.},
year = {2013}
}
TY - JOUR T1 - Diversity, Bioactivity and Drug Development of Cultivable Actinobacteria in Six Species of Bird Feces AU - Xiu Chen AU - Shumei Qiu AU - Yi Jiang AU - Li Han AU - Xueshi Huang AU - Chenglin Jiang Y1 - 2013/12/30 PY - 2013 N1 - https://doi.org/10.11648/j.ajbio.20140201.13 DO - 10.11648/j.ajbio.20140201.13 T2 - American Journal of BioScience JF - American Journal of BioScience JO - American Journal of BioScience SP - 13 EP - 18 PB - Science Publishing Group SN - 2330-0167 UR - https://doi.org/10.11648/j.ajbio.20140201.13 AB - In order to provide new lead compounds of drugs and other useful products, the diversity and some bioactivities of cultivable actinobacteria in bird feces were studied．Six species of bird fecal samples were collected from Yunnan Wild Animal Park and bank of Dian Lake. The pure cultures of actinobacteria were isolated from these samples by using 6 different media. The partial 16S rRNA gene sequences of 207 selected strains were determined, the phylogenetic analysis was carried out, and antimicrobial activities were determined by using agar diffusion method. The key biosynthase genes (CYP, AHBA and SAL) of antibiotics were also detected. Total 28 genera of actinobacteria from all the samples were identified. 18 genera were identified from Pavo cristatus feces, and the actinomycete community was the most complex. These actinobacteria had wide inhibition against 10 test microbes. In 30, 25, and 36 strains of actinobacteria isolated from Pavo cristatus, Grus japonensis and Larus ridibundus feces respectively, average 22.2%, 8.9% and 40.8% strains had the key biosynthase genes encoding CYP, AHBA and SAL. More than 30 bioactive secondary metabolites from several actinomycete strains of bird feces were isolated and characterized. The study shows that birds fecal actinobacteria are a new potential source for discovering new drugs and other industry products. VL - 2 IS - 1 ER -
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