An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation

Zhufu Shao; Ruirui Xu; Chunyan Yang

doi:doi:10.11648/j.sjph.20190706.14

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An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation

Zhufu Shao, Ruirui Xu, Chunyan Yang

Published in Science Journal of Public Health (Volume 7, Issue 6)

Received: 23 September 2019 Published: 18 November 2019

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Abstract

Objective To discuss the regularity in fasting blood sugar variations following kidneytransplantation and evaluate the PTDM morbidity and the effect of fasting blood sugar on survival and complications of patients. Method 422 patients receiving kidneytransplantation in our hospital from January 2015 to December 2018 were collected. Based on the pre-operative fasting blood sugar, the patients were divided into Group DM, IFG, and NFG. The variation trends of fasting blood sugar in various groups were obtained by analysing the fasting blood sugar data of patients 3, 6, 9, 12, 24, 36, 48, and 60 months before and after operation. The PTDM occurrence conditions were analysed 3, 6, 9, 12, 36, and 60 months after operation based on the fasting blood sugar of patients; a simplified OGTT was performed for patients with their fasting blood sugar not meeting the diagnostic criteria for diabetes ≥3 years after kidneytransplantation to analyse the PTDM morbidity among patients ≥3 years after kidneytransplantation and calculate the HOMA index. The patients were divided into Group DM, IFG, and NFG based on fasting blood sugar before kidneytransplantation and PTDM Group and Non-PTDM Group. A comparison was made for the difference in survival rate among various groups. Result The fasting blood sugar in the Group DM decreased significantly compared with that before operation (P<0.05); the fasting blood sugar in the Group IFG and NFG increased compared that before operation (P<0.05). The PTDM morbidity exhibited an overall decreasing trend with time and reached as high as 52.82% 3 months after operation. HOMA-IR was the highest in Group IGR followed by Group PTDM. HOMA-IR significantly increased in Group IGR compared with the group of normal blood sugar (P<0.05). HOMA-β in Group PTDM decreased significantly compared with the group of normal blood sugar and Group IGR (P<0.05). The survival rate in Group DM significantly decreased compared with that in Group NFG (P<0.05); the survival rate in Group IFG also decreased significantly compared with that in Group NFG (P<0.05); the average survival time and survival rate in Group PTDM were significantly lower than those in groups other than Group PTDM (P<0.05). Conclusion kidneytransplantation is able to improve the fasting blood sugar of patients with diabetes and the blood sugar can significant affect the survival rate of kidneytransplantation patients and lower the survival rate of patients.

Published in	Science Journal of Public Health (Volume 7, Issue 6)
DOI	10.11648/j.sjph.20190706.14
Page(s)	200-205
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Kidneytransplantation, Fasting Blood Sugar, Post-Transplant Diabetes, Survival

References

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[17]	Ollech JE. Kramer MR. et al. Post-transplant diabetes mellitus in lung transplant recipients: incidence and risk factors [J]. Eur J Cardiothorac Surg, 2018, 33 (5): 844-8.
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[30]	Veldt BJ. Duarte-Rojo A. et al. Recipient IL28B polymorphism is an important independent predictor of posttransplant diabetes mellitus in kidneytransplant patients with chronic hepatitis C [J]. Am J Transplant, 2019, 12 (3): 737-44.

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APA Style

Zhufu Shao, Ruirui Xu, Chunyan Yang. (2019). An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation. Science Journal of Public Health, 7(6), 200-205. https://doi.org/10.11648/j.sjph.20190706.14

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ACS Style

Zhufu Shao; Ruirui Xu; Chunyan Yang. An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation. Sci. J. Public Health 2019, 7(6), 200-205. doi: 10.11648/j.sjph.20190706.14

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AMA Style

Zhufu Shao, Ruirui Xu, Chunyan Yang. An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation. Sci J Public Health. 2019;7(6):200-205. doi: 10.11648/j.sjph.20190706.14

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@article{10.11648/j.sjph.20190706.14,
  author = {Zhufu Shao and Ruirui Xu and Chunyan Yang},
  title = {An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation},
  journal = {Science Journal of Public Health},
  volume = {7},
  number = {6},
  pages = {200-205},
  doi = {10.11648/j.sjph.20190706.14},
  url = {https://doi.org/10.11648/j.sjph.20190706.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20190706.14},
  abstract = {Objective To discuss the regularity in fasting blood sugar variations following kidneytransplantation and evaluate the PTDM morbidity and the effect of fasting blood sugar on survival and complications of patients. Method 422 patients receiving kidneytransplantation in our hospital from January 2015 to December 2018 were collected. Based on the pre-operative fasting blood sugar, the patients were divided into Group DM, IFG, and NFG. The variation trends of fasting blood sugar in various groups were obtained by analysing the fasting blood sugar data of patients 3, 6, 9, 12, 24, 36, 48, and 60 months before and after operation. The PTDM occurrence conditions were analysed 3, 6, 9, 12, 36, and 60 months after operation based on the fasting blood sugar of patients; a simplified OGTT was performed for patients with their fasting blood sugar not meeting the diagnostic criteria for diabetes ≥3 years after kidneytransplantation to analyse the PTDM morbidity among patients ≥3 years after kidneytransplantation and calculate the HOMA index. The patients were divided into Group DM, IFG, and NFG based on fasting blood sugar before kidneytransplantation and PTDM Group and Non-PTDM Group. A comparison was made for the difference in survival rate among various groups. Result The fasting blood sugar in the Group DM decreased significantly compared with that before operation (P<0.05); the fasting blood sugar in the Group IFG and NFG increased compared that before operation (P<0.05). The PTDM morbidity exhibited an overall decreasing trend with time and reached as high as 52.82% 3 months after operation. HOMA-IR was the highest in Group IGR followed by Group PTDM. HOMA-IR significantly increased in Group IGR compared with the group of normal blood sugar (P<0.05). HOMA-β in Group PTDM decreased significantly compared with the group of normal blood sugar and Group IGR (P<0.05). The survival rate in Group DM significantly decreased compared with that in Group NFG (P<0.05); the survival rate in Group IFG also decreased significantly compared with that in Group NFG (P<0.05); the average survival time and survival rate in Group PTDM were significantly lower than those in groups other than Group PTDM (P<0.05). Conclusion kidneytransplantation is able to improve the fasting blood sugar of patients with diabetes and the blood sugar can significant affect the survival rate of kidneytransplantation patients and lower the survival rate of patients.},
 year = {2019}
}

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TY  - JOUR
T1  - An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation
AU  - Zhufu Shao
AU  - Ruirui Xu
AU  - Chunyan Yang
Y1  - 2019/11/18
PY  - 2019
N1  - https://doi.org/10.11648/j.sjph.20190706.14
DO  - 10.11648/j.sjph.20190706.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 200
EP  - 205
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20190706.14
AB  - Objective To discuss the regularity in fasting blood sugar variations following kidneytransplantation and evaluate the PTDM morbidity and the effect of fasting blood sugar on survival and complications of patients. Method 422 patients receiving kidneytransplantation in our hospital from January 2015 to December 2018 were collected. Based on the pre-operative fasting blood sugar, the patients were divided into Group DM, IFG, and NFG. The variation trends of fasting blood sugar in various groups were obtained by analysing the fasting blood sugar data of patients 3, 6, 9, 12, 24, 36, 48, and 60 months before and after operation. The PTDM occurrence conditions were analysed 3, 6, 9, 12, 36, and 60 months after operation based on the fasting blood sugar of patients; a simplified OGTT was performed for patients with their fasting blood sugar not meeting the diagnostic criteria for diabetes ≥3 years after kidneytransplantation to analyse the PTDM morbidity among patients ≥3 years after kidneytransplantation and calculate the HOMA index. The patients were divided into Group DM, IFG, and NFG based on fasting blood sugar before kidneytransplantation and PTDM Group and Non-PTDM Group. A comparison was made for the difference in survival rate among various groups. Result The fasting blood sugar in the Group DM decreased significantly compared with that before operation (P<0.05); the fasting blood sugar in the Group IFG and NFG increased compared that before operation (P<0.05). The PTDM morbidity exhibited an overall decreasing trend with time and reached as high as 52.82% 3 months after operation. HOMA-IR was the highest in Group IGR followed by Group PTDM. HOMA-IR significantly increased in Group IGR compared with the group of normal blood sugar (P<0.05). HOMA-β in Group PTDM decreased significantly compared with the group of normal blood sugar and Group IGR (P<0.05). The survival rate in Group DM significantly decreased compared with that in Group NFG (P<0.05); the survival rate in Group IFG also decreased significantly compared with that in Group NFG (P<0.05); the average survival time and survival rate in Group PTDM were significantly lower than those in groups other than Group PTDM (P<0.05). Conclusion kidneytransplantation is able to improve the fasting blood sugar of patients with diabetes and the blood sugar can significant affect the survival rate of kidneytransplantation patients and lower the survival rate of patients.
VL  - 7
IS  - 6
ER  -

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Author Information

Zhufu Shao

Department of Critical Care Medicine, Binzhou People's Hospital, Binzhou City, P. R. China
Ruirui Xu

Department of Nephrology, Binzhou People's Hospital, Binzhou City, P. R. China
Chunyan Yang

Department of Critical Care Medicine, Binzhou People's Hospital, Binzhou City, P. R. China

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Plain Text BibTeX RIS

APA Style

Zhufu Shao, Ruirui Xu, Chunyan Yang. (2019). An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation. Science Journal of Public Health, 7(6), 200-205. https://doi.org/10.11648/j.sjph.20190706.14

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ACS Style

Zhufu Shao; Ruirui Xu; Chunyan Yang. An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation. Sci. J. Public Health 2019, 7(6), 200-205. doi: 10.11648/j.sjph.20190706.14

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AMA Style

Zhufu Shao, Ruirui Xu, Chunyan Yang. An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation. Sci J Public Health. 2019;7(6):200-205. doi: 10.11648/j.sjph.20190706.14

Copy | Download

@article{10.11648/j.sjph.20190706.14,
  author = {Zhufu Shao and Ruirui Xu and Chunyan Yang},
  title = {An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation},
  journal = {Science Journal of Public Health},
  volume = {7},
  number = {6},
  pages = {200-205},
  doi = {10.11648/j.sjph.20190706.14},
  url = {https://doi.org/10.11648/j.sjph.20190706.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20190706.14},
  abstract = {Objective To discuss the regularity in fasting blood sugar variations following kidneytransplantation and evaluate the PTDM morbidity and the effect of fasting blood sugar on survival and complications of patients. Method 422 patients receiving kidneytransplantation in our hospital from January 2015 to December 2018 were collected. Based on the pre-operative fasting blood sugar, the patients were divided into Group DM, IFG, and NFG. The variation trends of fasting blood sugar in various groups were obtained by analysing the fasting blood sugar data of patients 3, 6, 9, 12, 24, 36, 48, and 60 months before and after operation. The PTDM occurrence conditions were analysed 3, 6, 9, 12, 36, and 60 months after operation based on the fasting blood sugar of patients; a simplified OGTT was performed for patients with their fasting blood sugar not meeting the diagnostic criteria for diabetes ≥3 years after kidneytransplantation to analyse the PTDM morbidity among patients ≥3 years after kidneytransplantation and calculate the HOMA index. The patients were divided into Group DM, IFG, and NFG based on fasting blood sugar before kidneytransplantation and PTDM Group and Non-PTDM Group. A comparison was made for the difference in survival rate among various groups. Result The fasting blood sugar in the Group DM decreased significantly compared with that before operation (P<0.05); the fasting blood sugar in the Group IFG and NFG increased compared that before operation (P<0.05). The PTDM morbidity exhibited an overall decreasing trend with time and reached as high as 52.82% 3 months after operation. HOMA-IR was the highest in Group IGR followed by Group PTDM. HOMA-IR significantly increased in Group IGR compared with the group of normal blood sugar (P<0.05). HOMA-β in Group PTDM decreased significantly compared with the group of normal blood sugar and Group IGR (P<0.05). The survival rate in Group DM significantly decreased compared with that in Group NFG (P<0.05); the survival rate in Group IFG also decreased significantly compared with that in Group NFG (P<0.05); the average survival time and survival rate in Group PTDM were significantly lower than those in groups other than Group PTDM (P<0.05). Conclusion kidneytransplantation is able to improve the fasting blood sugar of patients with diabetes and the blood sugar can significant affect the survival rate of kidneytransplantation patients and lower the survival rate of patients.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - An Analysis of Regularity in Fasting Blood Sugar Variations and Influence Factors After Kidney Transplantation
AU  - Zhufu Shao
AU  - Ruirui Xu
AU  - Chunyan Yang
Y1  - 2019/11/18
PY  - 2019
N1  - https://doi.org/10.11648/j.sjph.20190706.14
DO  - 10.11648/j.sjph.20190706.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 200
EP  - 205
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20190706.14
AB  - Objective To discuss the regularity in fasting blood sugar variations following kidneytransplantation and evaluate the PTDM morbidity and the effect of fasting blood sugar on survival and complications of patients. Method 422 patients receiving kidneytransplantation in our hospital from January 2015 to December 2018 were collected. Based on the pre-operative fasting blood sugar, the patients were divided into Group DM, IFG, and NFG. The variation trends of fasting blood sugar in various groups were obtained by analysing the fasting blood sugar data of patients 3, 6, 9, 12, 24, 36, 48, and 60 months before and after operation. The PTDM occurrence conditions were analysed 3, 6, 9, 12, 36, and 60 months after operation based on the fasting blood sugar of patients; a simplified OGTT was performed for patients with their fasting blood sugar not meeting the diagnostic criteria for diabetes ≥3 years after kidneytransplantation to analyse the PTDM morbidity among patients ≥3 years after kidneytransplantation and calculate the HOMA index. The patients were divided into Group DM, IFG, and NFG based on fasting blood sugar before kidneytransplantation and PTDM Group and Non-PTDM Group. A comparison was made for the difference in survival rate among various groups. Result The fasting blood sugar in the Group DM decreased significantly compared with that before operation (P<0.05); the fasting blood sugar in the Group IFG and NFG increased compared that before operation (P<0.05). The PTDM morbidity exhibited an overall decreasing trend with time and reached as high as 52.82% 3 months after operation. HOMA-IR was the highest in Group IGR followed by Group PTDM. HOMA-IR significantly increased in Group IGR compared with the group of normal blood sugar (P<0.05). HOMA-β in Group PTDM decreased significantly compared with the group of normal blood sugar and Group IGR (P<0.05). The survival rate in Group DM significantly decreased compared with that in Group NFG (P<0.05); the survival rate in Group IFG also decreased significantly compared with that in Group NFG (P<0.05); the average survival time and survival rate in Group PTDM were significantly lower than those in groups other than Group PTDM (P<0.05). Conclusion kidneytransplantation is able to improve the fasting blood sugar of patients with diabetes and the blood sugar can significant affect the survival rate of kidneytransplantation patients and lower the survival rate of patients.
VL  - 7
IS  - 6
ER  -

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