Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism

Li Hongyan; Zhang Chunhui; Wang Hongsheng; Xu Qian

doi:doi:10.11648/j.sjph.20190705.14

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Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism

Li Hongyan, Zhang Chunhui, Wang Hongsheng, Xu Qian

Published in Science Journal of Public Health (Volume 7, Issue 5)

Received: 22 July 2019 Published: 27 September 2019

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Abstract

Objective: This paper is to explore the relationship between IL-2, IL-6, IL-8 and the development of hyperthyroidism and subclinical hyperthyroidism. Methods The serum levels of IL-2, IL-6 and IL-8 were determined in 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of normal control. Results The level of IL-2 in hyperthyroidism group was significantly lower than that in the control group (P<0.01), and the levels of IL-6 and IL-8 were significantly higher than those in the control group (P<0.01); The level of IL-2 in subclinical hyperthyroidism group was lower than that in the control group (P<0.05), and the levels of IL-6 and IL-8 were higher than those in the control group (P<0.05). The level of IL-2 in hyperthyroidism group was lower than that in subclinical hyperthyroidism group, and the level of IL-6 and IL-8 were higher than those in subclinical hyperthyroidism group. The two groups of IL-2 were negatively correlated with serum FT3, FT 4, TT3, and TT4, and IL-6 and IL-8 were positively correlated with serum FT3, FT 4, TT3, and TT4. Conclusions IL-2, IL-6, and IL-8 all participated in the development process of hyperthyroidism and subclinical hypothyroidism, which contributed to the early discovery of subclinical hyperthyroidism.

Published in	Science Journal of Public Health (Volume 7, Issue 5)
DOI	10.11648/j.sjph.20190705.14
Page(s)	159-162
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Hypothyroidism, Subclinical Hypothyroidism, IL-2, IL-6, IL-8

References

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APA Style

Li Hongyan, Zhang Chunhui, Wang Hongsheng, Xu Qian. (2019). Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism. Science Journal of Public Health, 7(5), 159-162. https://doi.org/10.11648/j.sjph.20190705.14

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ACS Style

Li Hongyan; Zhang Chunhui; Wang Hongsheng; Xu Qian. Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism. Sci. J. Public Health 2019, 7(5), 159-162. doi: 10.11648/j.sjph.20190705.14

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AMA Style

Li Hongyan, Zhang Chunhui, Wang Hongsheng, Xu Qian. Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism. Sci J Public Health. 2019;7(5):159-162. doi: 10.11648/j.sjph.20190705.14

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@article{10.11648/j.sjph.20190705.14,
  author = {Li Hongyan and Zhang Chunhui and Wang Hongsheng and Xu Qian},
  title = {Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism},
  journal = {Science Journal of Public Health},
  volume = {7},
  number = {5},
  pages = {159-162},
  doi = {10.11648/j.sjph.20190705.14},
  url = {https://doi.org/10.11648/j.sjph.20190705.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20190705.14},
  abstract = {Objective: This paper is to explore the relationship between IL-2, IL-6, IL-8 and the development of hyperthyroidism and subclinical hyperthyroidism. Methods The serum levels of IL-2, IL-6 and IL-8 were determined in 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of normal control. Results The level of IL-2 in hyperthyroidism group was significantly lower than that in the control group (P<0.01), and the levels of IL-6 and IL-8 were significantly higher than those in the control group (P<0.01); The level of IL-2 in subclinical hyperthyroidism group was lower than that in the control group (P<0.05), and the levels of IL-6 and IL-8 were higher than those in the control group (P<0.05). The level of IL-2 in hyperthyroidism group was lower than that in subclinical hyperthyroidism group, and the level of IL-6 and IL-8 were higher than those in subclinical hyperthyroidism group. The two groups of IL-2 were negatively correlated with serum FT3, FT 4, TT3, and TT4, and IL-6 and IL-8 were positively correlated with serum FT3, FT 4, TT3, and TT4. Conclusions IL-2, IL-6, and IL-8 all participated in the development process of hyperthyroidism and subclinical hypothyroidism, which contributed to the early discovery of subclinical hyperthyroidism.},
 year = {2019}
}

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TY  - JOUR
T1  - Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism
AU  - Li Hongyan
AU  - Zhang Chunhui
AU  - Wang Hongsheng
AU  - Xu Qian
Y1  - 2019/09/27
PY  - 2019
N1  - https://doi.org/10.11648/j.sjph.20190705.14
DO  - 10.11648/j.sjph.20190705.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 159
EP  - 162
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20190705.14
AB  - Objective: This paper is to explore the relationship between IL-2, IL-6, IL-8 and the development of hyperthyroidism and subclinical hyperthyroidism. Methods The serum levels of IL-2, IL-6 and IL-8 were determined in 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of normal control. Results The level of IL-2 in hyperthyroidism group was significantly lower than that in the control group (P<0.01), and the levels of IL-6 and IL-8 were significantly higher than those in the control group (P<0.01); The level of IL-2 in subclinical hyperthyroidism group was lower than that in the control group (P<0.05), and the levels of IL-6 and IL-8 were higher than those in the control group (P<0.05). The level of IL-2 in hyperthyroidism group was lower than that in subclinical hyperthyroidism group, and the level of IL-6 and IL-8 were higher than those in subclinical hyperthyroidism group. The two groups of IL-2 were negatively correlated with serum FT3, FT 4, TT3, and TT4, and IL-6 and IL-8 were positively correlated with serum FT3, FT 4, TT3, and TT4. Conclusions IL-2, IL-6, and IL-8 all participated in the development process of hyperthyroidism and subclinical hypothyroidism, which contributed to the early discovery of subclinical hyperthyroidism.
VL  - 7
IS  - 5
ER  -

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Author Information

Li Hongyan

Department of Medical Technology, Cangzhou Medical College, Cangzhou, China
Zhang Chunhui

Department of Blood Transfusion of Hejian People's Hospital, Cangzhou, China
Wang Hongsheng

Thyroid Diagnosis and Treatment Center of Cangzhou Traditional Chinese Medicine-Western Hospital, Cangzhou, China
Xu Qian

Department of Medical Technology, Cangzhou Medical College, Cangzhou, China

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APA Style

Li Hongyan, Zhang Chunhui, Wang Hongsheng, Xu Qian. (2019). Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism. Science Journal of Public Health, 7(5), 159-162. https://doi.org/10.11648/j.sjph.20190705.14

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ACS Style

Li Hongyan; Zhang Chunhui; Wang Hongsheng; Xu Qian. Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism. Sci. J. Public Health 2019, 7(5), 159-162. doi: 10.11648/j.sjph.20190705.14

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AMA Style

Li Hongyan, Zhang Chunhui, Wang Hongsheng, Xu Qian. Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism. Sci J Public Health. 2019;7(5):159-162. doi: 10.11648/j.sjph.20190705.14

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@article{10.11648/j.sjph.20190705.14,
  author = {Li Hongyan and Zhang Chunhui and Wang Hongsheng and Xu Qian},
  title = {Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism},
  journal = {Science Journal of Public Health},
  volume = {7},
  number = {5},
  pages = {159-162},
  doi = {10.11648/j.sjph.20190705.14},
  url = {https://doi.org/10.11648/j.sjph.20190705.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20190705.14},
  abstract = {Objective: This paper is to explore the relationship between IL-2, IL-6, IL-8 and the development of hyperthyroidism and subclinical hyperthyroidism. Methods The serum levels of IL-2, IL-6 and IL-8 were determined in 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of normal control. Results The level of IL-2 in hyperthyroidism group was significantly lower than that in the control group (P<0.01), and the levels of IL-6 and IL-8 were significantly higher than those in the control group (P<0.01); The level of IL-2 in subclinical hyperthyroidism group was lower than that in the control group (P<0.05), and the levels of IL-6 and IL-8 were higher than those in the control group (P<0.05). The level of IL-2 in hyperthyroidism group was lower than that in subclinical hyperthyroidism group, and the level of IL-6 and IL-8 were higher than those in subclinical hyperthyroidism group. The two groups of IL-2 were negatively correlated with serum FT3, FT 4, TT3, and TT4, and IL-6 and IL-8 were positively correlated with serum FT3, FT 4, TT3, and TT4. Conclusions IL-2, IL-6, and IL-8 all participated in the development process of hyperthyroidism and subclinical hypothyroidism, which contributed to the early discovery of subclinical hyperthyroidism.},
 year = {2019}
}

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TY  - JOUR
T1  - Significance of Serum IL-2, IL-6 and IL-8 Detection in Patients with Hyperthyroidism and Subclinical Hyperthyroidism
AU  - Li Hongyan
AU  - Zhang Chunhui
AU  - Wang Hongsheng
AU  - Xu Qian
Y1  - 2019/09/27
PY  - 2019
N1  - https://doi.org/10.11648/j.sjph.20190705.14
DO  - 10.11648/j.sjph.20190705.14
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 159
EP  - 162
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20190705.14
AB  - Objective: This paper is to explore the relationship between IL-2, IL-6, IL-8 and the development of hyperthyroidism and subclinical hyperthyroidism. Methods The serum levels of IL-2, IL-6 and IL-8 were determined in 251 cases of hyperthyroidism, 242 cases of subclinical hyperthyroidism and 130 cases of normal control. Results The level of IL-2 in hyperthyroidism group was significantly lower than that in the control group (P<0.01), and the levels of IL-6 and IL-8 were significantly higher than those in the control group (P<0.01); The level of IL-2 in subclinical hyperthyroidism group was lower than that in the control group (P<0.05), and the levels of IL-6 and IL-8 were higher than those in the control group (P<0.05). The level of IL-2 in hyperthyroidism group was lower than that in subclinical hyperthyroidism group, and the level of IL-6 and IL-8 were higher than those in subclinical hyperthyroidism group. The two groups of IL-2 were negatively correlated with serum FT3, FT 4, TT3, and TT4, and IL-6 and IL-8 were positively correlated with serum FT3, FT 4, TT3, and TT4. Conclusions IL-2, IL-6, and IL-8 all participated in the development process of hyperthyroidism and subclinical hypothyroidism, which contributed to the early discovery of subclinical hyperthyroidism.
VL  - 7
IS  - 5
ER  -

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