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Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020

Received: 17 December 2021     Accepted: 6 January 2022     Published: 18 March 2022
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Abstract

Acute kidney injury (AKI) is the sudden loss of organ function and the third leading cause of mortality after bleeding and brain trauma among admitted patients. There is a paucity of epidemiological data concerning AKI in Sub-Saharan African countries including Ethiopia with predominant admission of chronic cases. Methods: An institution-based cross-sectional study was conducted from 15 August- 14 October 2020. Epi-Data version 3.2 was used for data entry. In addition, STATA/14 was used for analysis. A Logistic regression model was used to determine the association of independent variables with the outcome variable and adjusted odds ratios (AOR) with 95% confidence interval was used to estimate the strength of the association at P<0.05. Result: Two hundred eighty-eight (288) card of inpatient were selected for analysis making the overall response rate 97.8%. The mean (±SD) age of the respondents was 44.16 (±18.29) years. The overall magnitude of AKI was 23.32% (95%CI: 18.91--29.36). Cases at baseline having hemoglobin level≤10.9mg/dl (AOR=11.4: 95%CI: 4.2, 31.2), bing cancer cases 6.87 (AOR=6.87; 95%CI: 1.76--26.73, P<0.005), and having creatinin levels > 1.36 mg/dl (>121 Micromole/L) was 5.78 (AOR=5.77; 95%CI: 1.93--17.27), were significantly associated with AKI. Conclusions: According to KDIGO-definitions of AKI, the high magnitude was reported among hospitalized patients and predicted by being cases of cancer, anemic and creatinine levels were significantly associated with AKI.

Published in Science Journal of Clinical Medicine (Volume 11, Issue 1)
DOI 10.11648/j.sjcm.20221101.15
Page(s) 33-39
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Acute Kidney Injury, Glomerular Filtration, Comorbidity, Ethiopia

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  • APA Style

    Desalagn Wegaso, Maekel Belay, Fassikaw Kebede. (2022). Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020. Science Journal of Clinical Medicine, 11(1), 33-39. https://doi.org/10.11648/j.sjcm.20221101.15

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    ACS Style

    Desalagn Wegaso; Maekel Belay; Fassikaw Kebede. Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020. Sci. J. Clin. Med. 2022, 11(1), 33-39. doi: 10.11648/j.sjcm.20221101.15

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    AMA Style

    Desalagn Wegaso, Maekel Belay, Fassikaw Kebede. Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020. Sci J Clin Med. 2022;11(1):33-39. doi: 10.11648/j.sjcm.20221101.15

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  • @article{10.11648/j.sjcm.20221101.15,
      author = {Desalagn Wegaso and Maekel Belay and Fassikaw Kebede},
      title = {Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020},
      journal = {Science Journal of Clinical Medicine},
      volume = {11},
      number = {1},
      pages = {33-39},
      doi = {10.11648/j.sjcm.20221101.15},
      url = {https://doi.org/10.11648/j.sjcm.20221101.15},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20221101.15},
      abstract = {Acute kidney injury (AKI) is the sudden loss of organ function and the third leading cause of mortality after bleeding and brain trauma among admitted patients. There is a paucity of epidemiological data concerning AKI in Sub-Saharan African countries including Ethiopia with predominant admission of chronic cases. Methods: An institution-based cross-sectional study was conducted from 15 August- 14 October 2020. Epi-Data version 3.2 was used for data entry. In addition, STATA/14 was used for analysis. A Logistic regression model was used to determine the association of independent variables with the outcome variable and adjusted odds ratios (AOR) with 95% confidence interval was used to estimate the strength of the association at P 1.36 mg/dl (>121 Micromole/L) was 5.78 (AOR=5.77; 95%CI: 1.93--17.27), were significantly associated with AKI. Conclusions: According to KDIGO-definitions of AKI, the high magnitude was reported among hospitalized patients and predicted by being cases of cancer, anemic and creatinine levels were significantly associated with AKI.},
     year = {2022}
    }
    

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    T1  - Magnitude and Factors Associated with Acute Kidney Injury Among Patients Admitted in Jimma University Medical Centre South West Ethiopia 2020
    AU  - Desalagn Wegaso
    AU  - Maekel Belay
    AU  - Fassikaw Kebede
    Y1  - 2022/03/18
    PY  - 2022
    N1  - https://doi.org/10.11648/j.sjcm.20221101.15
    DO  - 10.11648/j.sjcm.20221101.15
    T2  - Science Journal of Clinical Medicine
    JF  - Science Journal of Clinical Medicine
    JO  - Science Journal of Clinical Medicine
    SP  - 33
    EP  - 39
    PB  - Science Publishing Group
    SN  - 2327-2732
    UR  - https://doi.org/10.11648/j.sjcm.20221101.15
    AB  - Acute kidney injury (AKI) is the sudden loss of organ function and the third leading cause of mortality after bleeding and brain trauma among admitted patients. There is a paucity of epidemiological data concerning AKI in Sub-Saharan African countries including Ethiopia with predominant admission of chronic cases. Methods: An institution-based cross-sectional study was conducted from 15 August- 14 October 2020. Epi-Data version 3.2 was used for data entry. In addition, STATA/14 was used for analysis. A Logistic regression model was used to determine the association of independent variables with the outcome variable and adjusted odds ratios (AOR) with 95% confidence interval was used to estimate the strength of the association at P 1.36 mg/dl (>121 Micromole/L) was 5.78 (AOR=5.77; 95%CI: 1.93--17.27), were significantly associated with AKI. Conclusions: According to KDIGO-definitions of AKI, the high magnitude was reported among hospitalized patients and predicted by being cases of cancer, anemic and creatinine levels were significantly associated with AKI.
    VL  - 11
    IS  - 1
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Author Information
  • Units of Internal Medicine, Faculty of Medical Science, Institute of Health, Jimma University, Jimma, Ethiopia

  • Units of Internal Medicine, Faculty of Medical Science, Institute of Health, Jimma University, Jimma, Ethiopia

  • Department of Epidemiology and Biostatics, School of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia

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