PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish

Liu Zheng; Du Jia; Wang Shutao; You Hong

doi:doi:10.11648/j.sd.20160404.15

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PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish

Liu Zheng, Du Jia, Wang Shutao, You Hong

Published in Science Discovery (Volume 4, Issue 4)

Received: 19 July 2016 Published: 20 July 2016

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Abstract

Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.

Published in	Science Discovery (Volume 4, Issue 4)
DOI	10.11648/j.sd.20160404.15
Page(s)	232-237
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Perfluorooctanesul Phonic Acid Potassium Salt (PFOS), ZnO Nanoparticles (Nano-ZnO), Oxidative Stress, Joint Toxicity

References

[1]	Dong Y Y, Lei B L, Zhang C B, etal. Joint toxicity on multi-component mixtures of SDS and substituted aromatic compounds [J]. Environmental Science, 2006, 27: 1643-1646.
[2]	Yang Y B, Liu Z T, Hu Z J, etal. Study on the effect of joint biochemical toxicities of halophenols in Carassius aurat us [J]. Research of Environmental Sciences,2007, 20: 1-4.
[3]	Hu Z B, Wang H Z, Wu J J, etal. Ecological effects of both single and combined pollution of Cd and bensulfuron-methyl on soil microorganisms [J]. Journal of Zhejiang University: Agriculture & Life Sciences, 2005, 31(2): 151-156.
[4]	覃爱苗,廖雷.纳米技术及纳米材料在环境治理中的应[J].中山大学学报(自然科学版),2004,43(增刊):225-228。
[5]	Sakamoto J H, van de Ven A L, Godin B, etal. Enabling individualized therapy through nanotechnology [J]. Pharmacological Ｒesearch, 2010, 62(2): 57-89．
[6]	吕丽娜.纳米ZnO对斑马鱼胚胎的发育毒性研究［D］.哈尔滨:哈尔滨工业大学,2013。
[7]	Hao L H， Chen L. Oxidative stress responses in different organs of carp (Cyprinus carpio) with exposure to ZnO nanoparticles [J]. Ecotoxicology and Environmental Safety, 2012, 80: 103-110.
[8]	Sharma V, Singh P, Pandey A K, etal. Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles [J]. Mutation Ｒesearch, 2012, 745: 84-91.
[9]	Lau C, Butenhoff J L, Rogers J M. The developmental toxicity of perfluoroalkyl acids and their derivatives [J]. Toxicol Appl Pharmacol, 2004, 198(15): 231-241.
[10]	Maestri L, Negri S, Ferrari M, etal. Determination of perfluorooctanoic acid and perfluorooctanesulfonate in human tissues by liquid chromatography single quadrupole mass spectrometry [J]. Rapid Commun Mass Spectrom, 2006, 20(18): 2728-2734.
[11]	Wania F. A Global mass balance analysis of the source of perfluorocarboxylic acids in the Arctic ocean [J]. Environ Sci Technol, 2007, 41(13): 4529-4535.
[12]	周启星,胡献刚.PFOS/PFOA环境污染行为与毒性效应及机理研究进展[J].环境科学,2007,28(10):2153-2162。
[13]	胡芹,周珍,周群芳.全氟辛烷磺酸（PFOS）急性暴露对斑马鱼鳃显微结构的影响[J].生态毒理学报,2009,4(4):530-536。
[14]	徐立红,张甬元,陈宜瑜.分子生态毒理学研究进展及其在水环境保护中的意义[J].水生生物学报,1995,19(2):171-185。
[15]	Morales A E, Pérez-Jiménez A, Hidalog M C, etal. Oxidative stress and antioxidant defenses after prolonged starvation in Dentex dentex liver [J]. Comparative Biochemistry and Physiology. Toxicology & Pharmacology, 2004, 139(1): 153-161.
[16]	罗义,施华宏,王晓蓉,等.2,4-二氯苯酚诱导鲫鱼肝脏自由基的产生和脂质过氧化[J].环境科学,2005,26(3):29-32。
[17]	胡玲,林玉锁.呋喃丹对赤子爱胜蚓体内蛋白含量、SOD和TChE活性的影响[J].安徽农业科学,2006,34(13):3165-3167。
[18]	刘林,赵群芬,等.纳米氧化锌对斑马鱼肝脏的毒性效应[J].环境科学,2015,36(10):3884-3891。
[19]	孙诗博,李武,等.PFOS对斑马鱼胚胎发育及SOD、MDA和GSH含量的影响[J].实用预防医学,2015,22(6):648-651。
[20]	Ma L L, Liu J, Li N, etal. Oxidative stress in the brain of mice caused by translocated nanoparticulate TiO2 delivered to the abdominal cavity[J]. Biomaterial, 2010, 31: 99-105.
[21]	Hu W Y, Jones P D, De Coen W, King L, Fraker P, Newsted J, Giesy J P. Alterations in cellmembrane properties caused by perfluorinatedcompounds. Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology, 2003, 135(1): 77-88．
[22]	Harada K, Xu F, Ono K, Iijima T, Koizumi A. Effects of PFOS and PFOA on L-type Ca2+currents in guinea-pig ventricular myocytes. Biochemicaland BiophysicalＲesearch Communications, 2005, 329(2): 487-494.

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APA Style

Liu Zheng, Du Jia, Wang Shutao, You Hong. (2016). PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Science Discovery, 4(4), 232-237. https://doi.org/10.11648/j.sd.20160404.15

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ACS Style

Liu Zheng; Du Jia; Wang Shutao; You Hong. PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Sci. Discov. 2016, 4(4), 232-237. doi: 10.11648/j.sd.20160404.15

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AMA Style

Liu Zheng, Du Jia, Wang Shutao, You Hong. PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Sci Discov. 2016;4(4):232-237. doi: 10.11648/j.sd.20160404.15

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@article{10.11648/j.sd.20160404.15,
  author = {Liu Zheng and Du Jia and Wang Shutao and You Hong},
  title = {PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish},
  journal = {Science Discovery},
  volume = {4},
  number = {4},
  pages = {232-237},
  doi = {10.11648/j.sd.20160404.15},
  url = {https://doi.org/10.11648/j.sd.20160404.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20160404.15},
  abstract = {Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.},
 year = {2016}
}

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TY  - JOUR
T1  - PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish
AU  - Liu Zheng
AU  - Du Jia
AU  - Wang Shutao
AU  - You Hong
Y1  - 2016/07/20
PY  - 2016
N1  - https://doi.org/10.11648/j.sd.20160404.15
DO  - 10.11648/j.sd.20160404.15
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 232
EP  - 237
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20160404.15
AB  - Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.
VL  - 4
IS  - 4
ER  -

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Author Information

Liu Zheng

State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China
Du Jia

State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China
Wang Shutao

State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China
You Hong

School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Harbin, China

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Plain Text BibTeX RIS

APA Style

Liu Zheng, Du Jia, Wang Shutao, You Hong. (2016). PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Science Discovery, 4(4), 232-237. https://doi.org/10.11648/j.sd.20160404.15

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ACS Style

Liu Zheng; Du Jia; Wang Shutao; You Hong. PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Sci. Discov. 2016, 4(4), 232-237. doi: 10.11648/j.sd.20160404.15

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AMA Style

Liu Zheng, Du Jia, Wang Shutao, You Hong. PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish. Sci Discov. 2016;4(4):232-237. doi: 10.11648/j.sd.20160404.15

Copy | Download

@article{10.11648/j.sd.20160404.15,
  author = {Liu Zheng and Du Jia and Wang Shutao and You Hong},
  title = {PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish},
  journal = {Science Discovery},
  volume = {4},
  number = {4},
  pages = {232-237},
  doi = {10.11648/j.sd.20160404.15},
  url = {https://doi.org/10.11648/j.sd.20160404.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sd.20160404.15},
  abstract = {Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.},
 year = {2016}
}

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TY  - JOUR
T1  - PFOS and ZnO Nanoparticles Induced Oxidative Stress in Liver, Gill and Head of Zebrafish
AU  - Liu Zheng
AU  - Du Jia
AU  - Wang Shutao
AU  - You Hong
Y1  - 2016/07/20
PY  - 2016
N1  - https://doi.org/10.11648/j.sd.20160404.15
DO  - 10.11648/j.sd.20160404.15
T2  - Science Discovery
JF  - Science Discovery
JO  - Science Discovery
SP  - 232
EP  - 237
PB  - Science Publishing Group
SN  - 2331-0650
UR  - https://doi.org/10.11648/j.sd.20160404.15
AB  - Oxidative stress to liver, gill and head of zebrafish (Danio rerio) induced by perfluorooctanesul phonic acid potassium salt (PFOS) and ZnO nanoparticles (Nano-ZnO) is investigated in this study. Activities of superoxide dismutase (SOD), catalase (CAT) and malondialdehyde (MDA) contents were measured in liver, gill and head of zebrafish. The results demonstrated that both PFOS and Nano-ZnO single and co-exposure induced oxidative stress. In addition, PFOS plus Nano-ZnO exposure caused more serious oxidative stress than single-exposure at above exposure concentrations. Besides, compare with single-exposure, the activity of CAT is significantly lower, while the content of MDA is significantly higher in co-exposure solutions. The biochemical assays of head showed that, compare with single-exposure, co-exposure had more obvious effect on the activities of SOD, CAT and the content of MDA. Under the toxicity ratio of 1:1, Nano-ZnO increased the toxicity of PFOS on oxidative stress in liver, gill and head of zebrafish at the experimental concentrations.
VL  - 4
IS  - 4
ER  -

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