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Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak

Received: 13 November 2019     Accepted: 11 December 2019     Published: 23 December 2019
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Abstract

Spontaneous nasal liquorrhea is a pathological condition associated with defects between the nasal cavity and the intracranial structures, which results in CSF leak from the nasal cavity. Diagnostic criteria include: anamnesis, examination of the nasal fluid, endoscopic examination of the nasal cavity, and CT - and MRI - cisternography. Conservative therapy is applicable to small fistulas. In the case of the inefficiency of this method, surgical method is then applied to the defect closure. Purpose of the study: To evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment. Materials and methods: For the period from 2008 to 2018 at the Pavlov First Saint Petersburg State Medical University, at the clinic of neurosurgery of the Kirov Medical Institute and the Medical Research Center Almazov, 38 patients with spontaneous nasal liquorrhea were treated. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal approach. Results: In 4 cases, there was a large defect requiring secondary surgical intervention 1-2 weeks after the initial operation. Conclusions: The use of auto tissues (muscle or fat) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in the case of a large size defect.

Published in Journal of Surgery (Volume 7, Issue 6)
DOI 10.11648/j.js.20190706.19
Page(s) 198-201
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Nasal Liquorrhea, Skull Base, Autograph

References
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Cite This Article
  • APA Style

    Sergei Karpishchenko, Vladislav Cherebillo, Olga Vereshchagina, Nikita Puzakov, Olga Stancheva. (2019). Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak. Journal of Surgery, 7(6), 198-201. https://doi.org/10.11648/j.js.20190706.19

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    ACS Style

    Sergei Karpishchenko; Vladislav Cherebillo; Olga Vereshchagina; Nikita Puzakov; Olga Stancheva. Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak. J. Surg. 2019, 7(6), 198-201. doi: 10.11648/j.js.20190706.19

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    AMA Style

    Sergei Karpishchenko, Vladislav Cherebillo, Olga Vereshchagina, Nikita Puzakov, Olga Stancheva. Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak. J Surg. 2019;7(6):198-201. doi: 10.11648/j.js.20190706.19

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  • @article{10.11648/j.js.20190706.19,
      author = {Sergei Karpishchenko and Vladislav Cherebillo and Olga Vereshchagina and Nikita Puzakov and Olga Stancheva},
      title = {Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak},
      journal = {Journal of Surgery},
      volume = {7},
      number = {6},
      pages = {198-201},
      doi = {10.11648/j.js.20190706.19},
      url = {https://doi.org/10.11648/j.js.20190706.19},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190706.19},
      abstract = {Spontaneous nasal liquorrhea is a pathological condition associated with defects between the nasal cavity and the intracranial structures, which results in CSF leak from the nasal cavity. Diagnostic criteria include: anamnesis, examination of the nasal fluid, endoscopic examination of the nasal cavity, and CT - and MRI - cisternography. Conservative therapy is applicable to small fistulas. In the case of the inefficiency of this method, surgical method is then applied to the defect closure. Purpose of the study: To evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment. Materials and methods: For the period from 2008 to 2018 at the Pavlov First Saint Petersburg State Medical University, at the clinic of neurosurgery of the Kirov Medical Institute and the Medical Research Center Almazov, 38 patients with spontaneous nasal liquorrhea were treated. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal approach. Results: In 4 cases, there was a large defect requiring secondary surgical intervention 1-2 weeks after the initial operation. Conclusions: The use of auto tissues (muscle or fat) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in the case of a large size defect.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Transsphenoidal Endoscopic Approach in Treatment of Spontaneous Nasal CSF-leak
    AU  - Sergei Karpishchenko
    AU  - Vladislav Cherebillo
    AU  - Olga Vereshchagina
    AU  - Nikita Puzakov
    AU  - Olga Stancheva
    Y1  - 2019/12/23
    PY  - 2019
    N1  - https://doi.org/10.11648/j.js.20190706.19
    DO  - 10.11648/j.js.20190706.19
    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 198
    EP  - 201
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.20190706.19
    AB  - Spontaneous nasal liquorrhea is a pathological condition associated with defects between the nasal cavity and the intracranial structures, which results in CSF leak from the nasal cavity. Diagnostic criteria include: anamnesis, examination of the nasal fluid, endoscopic examination of the nasal cavity, and CT - and MRI - cisternography. Conservative therapy is applicable to small fistulas. In the case of the inefficiency of this method, surgical method is then applied to the defect closure. Purpose of the study: To evaluate the effectiveness of endoscopic endonasal approach in the CSF leak treatment. Materials and methods: For the period from 2008 to 2018 at the Pavlov First Saint Petersburg State Medical University, at the clinic of neurosurgery of the Kirov Medical Institute and the Medical Research Center Almazov, 38 patients with spontaneous nasal liquorrhea were treated. All patients underwent plastic surgery of the CSF fistula by endoscopic endonasal approach. Results: In 4 cases, there was a large defect requiring secondary surgical intervention 1-2 weeks after the initial operation. Conclusions: The use of auto tissues (muscle or fat) is the method of choice for repeated surgical plastics of the cerebrospinal fluid fistula or in the case of a large size defect.
    VL  - 7
    IS  - 6
    ER  - 

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Author Information
  • Department of Otorhinolaringology, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia

  • Department of Neurosurgery, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia

  • Department of Otorhinolaringology, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia

  • Department of Neurosurgery, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia

  • Department of Otorhinolaringology, Pavlov First Saint Petersburg State Medical University, St. Petersburg, Russia

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