Background: Gastric carcinoma in the bypassed stomach after Roux en Y gastric bypass (RYGB) is rare, a few cases have been reported since 1991. The symptomatology associated is non-specific and the monitoring of a bypassed stomach is difficult. Case presentation: We present a case of a 57-year-old woman with an early cancer in the bypassed stomach 1 year after bariatric surgery. Method: PubMed, Web of Science and EMBASE databases were revised. Result: up to date, 17 case reports are founded in literature, among theme 15 revealed gastric carcinoma, 1 GIST and 1 lymphoma. In our study were included 18 patients with gastric carcinoma. The interval between bypass surgery and the diagnosis of cancer ranged from 1 to 22 years. Mean patient age was 53.1 years (range: 38-71 years). The most frequent symptom was vague abdominal pain (50%), while only in one case was asymptomatic. In 7 patients (38,9%) the tumor was unresectable. Conclusion: Gastric carcinoma in the bypassed stomach after RYGB is rare and it is difficult to diagnose, and often disease’s stage is advanced by the time of diagnosis. The associated symptomalogy is non-specific, and so, it’s important to maintain a high clinical suspicion to diagnose it early.
Published in | Journal of Surgery (Volume 7, Issue 6) |
DOI | 10.11648/j.js.20190706.13 |
Page(s) | 163-167 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Bariatric Surgery, Gastric Cancer, Roux-en-Y Gastric Bypass, Bypassed Stomach
[1] | Raijman I, Strother SV, Donegan WL. Gastric cancer after gastric bypass for obesity. J Clin Gastroenterol 1991; 13: 191–194. |
[2] | Lord RV, Edwards PD, Coleman MJ. Gastric cancer in the bypassed segment after operation for morbid obesity. Aust NZ J Surg 1997; 67: 580–582. |
[3] | Khitin L, Roses R, Birkett D. Cancer in the gastric remnant after gastric bypass. Curr Surg 2003; 60: 521–523. |
[4] | Escalona A, Guzmán S, Ibáñez L et al. Gastric cancer after Roux-en-Y gastric bypass. Obes Surg 2005; 15: 423–427. |
[5] | Corsini DA, Simoneti CA, Moreira G et al. Cancer in the excluded stomach 4 years after gastric bypass. Obes Surg 2006; 16: 932–934. |
[6] | Harper JL, Beech D, Tichansky DS et al. Cancer in the bypassed stomach presenting early after gastric bypass. Obes Surg 2007; 17: 1268–1271. |
[7] | Swain JM, Adams RB, Farnell MB et al. Gatric and pancreatoduodenal resection for malignant lesions after previous gastric bypass-diagnosis and methods of reconstruction. Surg Obes Relat Dis. 2010; 6 (6): 670-5. |
[8] | Watkins BJ, Blackmun S, Kuehner ME. Gastric adenocarcinoma after Roux-en-Y gastric bypass: Access and evaluation of excluded stomach. Surg Obes Relat Dis 2007; 3: 644–647. |
[9] | Chun-Chi Wu, Wei-Jei Lee et al. Gastric cancer after mini-gastric bypass surgery: A case report and literature review. Asian J Endosc Surg ISSN 1758-5902. |
[10] | Menéndez P, Villarejo P and Padilla D. Krukenberg tumor after gastric bypass for morbid obesity. Bariatric surgery and gastric cancer. Rev esp enferm dig (Madrid) Vol. 105. N.° 5, pp. 296-298, 2013. |
[11] | Nau P, Rattner DW, Meireles O, Linitis plastic presenting two years after elective Roux-en-Y gastric bypass for treatment of morbid obesity: a case report and review of the literature. Surg Obes Relat Dis. 2014; 10 (2): e15-7. |
[12] | Tinoco A, Gottardi LF, and Boechat ED. Gastric Cancer in the Excluded Stomach 10 Years after Gastric Bypass. Case Reports in Surgery Volume 2015, Article ID 468293, 3 pages. |
[13] | D’Antonio A, Borgheresi P, Adesso M. An unexpected adverse event of gastric bypass: giant hyperplastic polyp showing an intramucosal adenocarcinoma. Gastrointest Endosc. 2017 Oct; 86 (4): 734-6. |
[14] | Ali S, Chaar A, Frandah W. Exploring the excluded stomach: a case series of novel endoscopic techniques to diagnose gastric cancer in the excluded stomach after Roux-en-Y gastric bypass surgery. Cureus 2018; 10 (6): e2825. |
[15] | Haenen FW, Gys B, Moreels T. Linitis plastic of the bypassed stomach 7 years after Roux-en-Y gastric bypass: a case report. Acta Chir Belg. 2017; 117 (6): 391-3. |
[16] | Abellan I, Ruiz de Angulo D, Parrilla P. Incidental gastric gastrointestinal stromal tumor (GIST) in the excluded stomach after Roux-en-Y gastric bypass: a case report and review of the literature. Surg Obes Relat Dis. 2014; 10 (1): e13-4. |
[17] | De Roover A, Detry O, de Leval L et al. Report of two cases of gastric cancer after bariatric surgery: lymphoma of the bypassed stomach after Roux-en-Y gastric bypass and gastrointestinal stromal tumor (GIST) after vertical banded gastroplasty. Obes Surg. 2006; 16: 928-31. |
[18] | Reinhold RB. Critical analysis of long-term weight loss following gastric bypass. Surg Gynecol Obstet. 1982; 155: 385-94. |
[19] | Maggard MA Shugarman LR, Suttorp M, Maglione M, Sugerman HJ, Livingston EH, et al. Meta-analysis: surgical treatment of obesity. Ann Intern Med. 2005; 142 (7): 547-59. |
[20] | Imura J et al Malignant transformation of hyperplastic gastric polyps: An immunohistochemical and pathological study of the changes of neoplastic phenotype. Oncol Lett. 2014 May; 7 (5): 1459–1463. |
[21] | Daibo M, Itabashi M, Hirota T. Malignant transformation of gastric hyperplastic polyps. Am J Gastroenterol. 1987; 82: 1016–1025. |
[22] | Zea-Iriarte WL, Sekine I, Itsuno M, et al. Carcinoma in gastric hyperplastic polyps. A phenotypic study. Dig Dis Sci. 1996; 41: 377–386. |
[23] | Orlowska J, Kupryjanczyk J. Malignant transformation of gastric hyperplastic polyps. Am J Clin Pathol. 2002; 117: 165–166. |
[24] | Spiegel A, Stein P, Patel M, Patel R, Lebovics E. A report of Gatric Fundic Gland Polyps. Gastroenterol Hepatol (N Y), 2010 Jan; 6 (1): 45-48. |
APA Style
Lancellotti Francesco, Coupaye Muriel, Dior Marie, Calabrese Daniela. (2019). Gastric Cancer After Roux-en-Y Gastric Bypass: A Case Report and a Systematic Review. Journal of Surgery, 7(6), 163-167. https://doi.org/10.11648/j.js.20190706.13
ACS Style
Lancellotti Francesco; Coupaye Muriel; Dior Marie; Calabrese Daniela. Gastric Cancer After Roux-en-Y Gastric Bypass: A Case Report and a Systematic Review. J. Surg. 2019, 7(6), 163-167. doi: 10.11648/j.js.20190706.13
AMA Style
Lancellotti Francesco, Coupaye Muriel, Dior Marie, Calabrese Daniela. Gastric Cancer After Roux-en-Y Gastric Bypass: A Case Report and a Systematic Review. J Surg. 2019;7(6):163-167. doi: 10.11648/j.js.20190706.13
@article{10.11648/j.js.20190706.13, author = {Lancellotti Francesco and Coupaye Muriel and Dior Marie and Calabrese Daniela}, title = {Gastric Cancer After Roux-en-Y Gastric Bypass: A Case Report and a Systematic Review}, journal = {Journal of Surgery}, volume = {7}, number = {6}, pages = {163-167}, doi = {10.11648/j.js.20190706.13}, url = {https://doi.org/10.11648/j.js.20190706.13}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190706.13}, abstract = {Background: Gastric carcinoma in the bypassed stomach after Roux en Y gastric bypass (RYGB) is rare, a few cases have been reported since 1991. The symptomatology associated is non-specific and the monitoring of a bypassed stomach is difficult. Case presentation: We present a case of a 57-year-old woman with an early cancer in the bypassed stomach 1 year after bariatric surgery. Method: PubMed, Web of Science and EMBASE databases were revised. Result: up to date, 17 case reports are founded in literature, among theme 15 revealed gastric carcinoma, 1 GIST and 1 lymphoma. In our study were included 18 patients with gastric carcinoma. The interval between bypass surgery and the diagnosis of cancer ranged from 1 to 22 years. Mean patient age was 53.1 years (range: 38-71 years). The most frequent symptom was vague abdominal pain (50%), while only in one case was asymptomatic. In 7 patients (38,9%) the tumor was unresectable. Conclusion: Gastric carcinoma in the bypassed stomach after RYGB is rare and it is difficult to diagnose, and often disease’s stage is advanced by the time of diagnosis. The associated symptomalogy is non-specific, and so, it’s important to maintain a high clinical suspicion to diagnose it early.}, year = {2019} }
TY - JOUR T1 - Gastric Cancer After Roux-en-Y Gastric Bypass: A Case Report and a Systematic Review AU - Lancellotti Francesco AU - Coupaye Muriel AU - Dior Marie AU - Calabrese Daniela Y1 - 2019/11/06 PY - 2019 N1 - https://doi.org/10.11648/j.js.20190706.13 DO - 10.11648/j.js.20190706.13 T2 - Journal of Surgery JF - Journal of Surgery JO - Journal of Surgery SP - 163 EP - 167 PB - Science Publishing Group SN - 2330-0930 UR - https://doi.org/10.11648/j.js.20190706.13 AB - Background: Gastric carcinoma in the bypassed stomach after Roux en Y gastric bypass (RYGB) is rare, a few cases have been reported since 1991. The symptomatology associated is non-specific and the monitoring of a bypassed stomach is difficult. Case presentation: We present a case of a 57-year-old woman with an early cancer in the bypassed stomach 1 year after bariatric surgery. Method: PubMed, Web of Science and EMBASE databases were revised. Result: up to date, 17 case reports are founded in literature, among theme 15 revealed gastric carcinoma, 1 GIST and 1 lymphoma. In our study were included 18 patients with gastric carcinoma. The interval between bypass surgery and the diagnosis of cancer ranged from 1 to 22 years. Mean patient age was 53.1 years (range: 38-71 years). The most frequent symptom was vague abdominal pain (50%), while only in one case was asymptomatic. In 7 patients (38,9%) the tumor was unresectable. Conclusion: Gastric carcinoma in the bypassed stomach after RYGB is rare and it is difficult to diagnose, and often disease’s stage is advanced by the time of diagnosis. The associated symptomalogy is non-specific, and so, it’s important to maintain a high clinical suspicion to diagnose it early. VL - 7 IS - 6 ER -