Background: Liver regeneration for donors' graft in living donor liver transplantation (LDLT), is an example for liver regeneration in normal liver. In this study we spotted the light on liver regeneration in donors after LDLT, focusing on factors affecting it. Aim: To study the impact of different factors on liver regeneration in donors of living donor liver transplantation. Patients and methods: Between May 2013 and June 2019, 80 living donor liver transplants were performed in the liver transplant unit in EL-Maadi Armed Forces Hospital. All donors who provided liver grafts underwent volumetric spiral computed tomography (CT) scans preoperatively and postoperatively at time intervals of 1 week and 1, 3 and 6 months. Patients’ demographics, surgical data, and postoperative outcomes were correlated with liver regeneration data. 63 patients were males and 17 patients were females, with mean age 27.97yrs ± 5.3. They provided {72} right lobe (RL) grafts and 8 right posterior sector (RP) grafts. Results: No donor operation was aborted and surgical morbidity rate was {33.75%}, mostly biliary. All RP donors achieved complete liver regeneration after 3 months; only four RL donors achieved complete liver regeneration at 6 months. Conclusion: In this study, it was found that there were factors affecting regeneration like age, gender of the patient and graft size. But no effect was found with many factors as peri-operative liver function tests, steatosis, BMI, operative time, blood loss, blood transfusion and postoperative complications.
| Published in | Journal of Surgery (Volume 7, Issue 4) |
| DOI | 10.11648/j.js.20190704.11 |
| Page(s) | 87-95 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Liver Transplantation, Liver Regeneration, Living Donors
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APA Style
Morsi Mohamed, Wael Mansy, Osama Khalil, Yehia Attwa, Magdy Amin, et al. (2019). Factors Affecting Liver Regeneration in Donors' Grafts in Living Donor Liver Transplant (LDLT) a Center Experience. Journal of Surgery, 7(4), 87-95. https://doi.org/10.11648/j.js.20190704.11
ACS Style
Morsi Mohamed; Wael Mansy; Osama Khalil; Yehia Attwa; Magdy Amin, et al. Factors Affecting Liver Regeneration in Donors' Grafts in Living Donor Liver Transplant (LDLT) a Center Experience. J. Surg. 2019, 7(4), 87-95. doi: 10.11648/j.js.20190704.11
AMA Style
Morsi Mohamed, Wael Mansy, Osama Khalil, Yehia Attwa, Magdy Amin, et al. Factors Affecting Liver Regeneration in Donors' Grafts in Living Donor Liver Transplant (LDLT) a Center Experience. J Surg. 2019;7(4):87-95. doi: 10.11648/j.js.20190704.11
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Download@article{10.11648/j.js.20190704.11,
author = {Morsi Mohamed and Wael Mansy and Osama Khalil and Yehia Attwa and Magdy Amin and Karim Boudjema},
title = {Factors Affecting Liver Regeneration in Donors' Grafts in Living Donor Liver Transplant (LDLT) a Center Experience},
journal = {Journal of Surgery},
volume = {7},
number = {4},
pages = {87-95},
doi = {10.11648/j.js.20190704.11},
url = {https://doi.org/10.11648/j.js.20190704.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190704.11},
abstract = {Background: Liver regeneration for donors' graft in living donor liver transplantation (LDLT), is an example for liver regeneration in normal liver. In this study we spotted the light on liver regeneration in donors after LDLT, focusing on factors affecting it. Aim: To study the impact of different factors on liver regeneration in donors of living donor liver transplantation. Patients and methods: Between May 2013 and June 2019, 80 living donor liver transplants were performed in the liver transplant unit in EL-Maadi Armed Forces Hospital. All donors who provided liver grafts underwent volumetric spiral computed tomography (CT) scans preoperatively and postoperatively at time intervals of 1 week and 1, 3 and 6 months. Patients’ demographics, surgical data, and postoperative outcomes were correlated with liver regeneration data. 63 patients were males and 17 patients were females, with mean age 27.97yrs ± 5.3. They provided {72} right lobe (RL) grafts and 8 right posterior sector (RP) grafts. Results: No donor operation was aborted and surgical morbidity rate was {33.75%}, mostly biliary. All RP donors achieved complete liver regeneration after 3 months; only four RL donors achieved complete liver regeneration at 6 months. Conclusion: In this study, it was found that there were factors affecting regeneration like age, gender of the patient and graft size. But no effect was found with many factors as peri-operative liver function tests, steatosis, BMI, operative time, blood loss, blood transfusion and postoperative complications.},
year = {2019}
}
TY - JOUR
T1 - Factors Affecting Liver Regeneration in Donors' Grafts in Living Donor Liver Transplant (LDLT) a Center Experience
AU - Morsi Mohamed
AU - Wael Mansy
AU - Osama Khalil
AU - Yehia Attwa
AU - Magdy Amin
AU - Karim Boudjema
Y1 - 2019/07/02
PY - 2019
N1 - https://doi.org/10.11648/j.js.20190704.11
DO - 10.11648/j.js.20190704.11
T2 - Journal of Surgery
JF - Journal of Surgery
JO - Journal of Surgery
SP - 87
EP - 95
PB - Science Publishing Group
SN - 2330-0930
UR - https://doi.org/10.11648/j.js.20190704.11
AB - Background: Liver regeneration for donors' graft in living donor liver transplantation (LDLT), is an example for liver regeneration in normal liver. In this study we spotted the light on liver regeneration in donors after LDLT, focusing on factors affecting it. Aim: To study the impact of different factors on liver regeneration in donors of living donor liver transplantation. Patients and methods: Between May 2013 and June 2019, 80 living donor liver transplants were performed in the liver transplant unit in EL-Maadi Armed Forces Hospital. All donors who provided liver grafts underwent volumetric spiral computed tomography (CT) scans preoperatively and postoperatively at time intervals of 1 week and 1, 3 and 6 months. Patients’ demographics, surgical data, and postoperative outcomes were correlated with liver regeneration data. 63 patients were males and 17 patients were females, with mean age 27.97yrs ± 5.3. They provided {72} right lobe (RL) grafts and 8 right posterior sector (RP) grafts. Results: No donor operation was aborted and surgical morbidity rate was {33.75%}, mostly biliary. All RP donors achieved complete liver regeneration after 3 months; only four RL donors achieved complete liver regeneration at 6 months. Conclusion: In this study, it was found that there were factors affecting regeneration like age, gender of the patient and graft size. But no effect was found with many factors as peri-operative liver function tests, steatosis, BMI, operative time, blood loss, blood transfusion and postoperative complications.
VL - 7
IS - 4
ER -
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