The quality and quantity of protein are essential factors that determine nutritional significance of a protein. The aim of this study was to compare the effects of several animal and plant proteins on the progression of renal failure in rats. Ninety male rats were allocated into nine groups and were fed with a basal diet containing different protein sources for 12 weeks. Two groups comprised of a negative control group and a positive control group (with induced renal failure) fed on the basal diet. Rats in the remaining seven groups were fed using different diets containing 10% protein derived from fish, meat, chicken, egg, soybean, lentil, and white bean. Biological, biochemical and histological studies were done at the end of the study. Protein content was highest for the chicken extract (87.36%), followed by meat (85.67%), egg (78.85%), and fish (78.55%). Body weight gain increased as food intake decreased in all groups other than the positive control group, and the food efficiency ratio paralleled food intake. Rats fed the fish protein diet had lower blood urea nitrogen (28.0 mg/dL), uric acid (3.5mg/dL) levels compared with the other groups. There were no significant differences in creatinine levels between rats fed the animal protein (fish and meat) or the plant protein (soy and white bean) diets. Histological studies revealed no abnormal renal features in rats fed the fish or soybean protein diets. Therefore, the results of the study suggest that a diet containing fish protein may delay the progression of chronic renal failure relative to other protein diets.
| Published in | Journal of Food and Nutrition Sciences (Volume 1, Issue 3) |
| DOI | 10.11648/j.jfns.20130103.11 |
| Page(s) | 23-32 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Animal Protein, Plant Protein, Rats, Renal Failure without Dialysis, Renal Function
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APA Style
Nadia Saleh Al-Amoudi. (2013). Effects of Dietary Protein Sources on the Progression of Renal Failure without Dialysis in Rats. Journal of Food and Nutrition Sciences, 1(3), 23-32. https://doi.org/10.11648/j.jfns.20130103.11
ACS Style
Nadia Saleh Al-Amoudi. Effects of Dietary Protein Sources on the Progression of Renal Failure without Dialysis in Rats. J. Food Nutr. Sci. 2013, 1(3), 23-32. doi: 10.11648/j.jfns.20130103.11
AMA Style
Nadia Saleh Al-Amoudi. Effects of Dietary Protein Sources on the Progression of Renal Failure without Dialysis in Rats. J Food Nutr Sci. 2013;1(3):23-32. doi: 10.11648/j.jfns.20130103.11
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Download@article{10.11648/j.jfns.20130103.11,
author = {Nadia Saleh Al-Amoudi},
title = {Effects of Dietary Protein Sources on the Progression of Renal Failure without Dialysis in Rats},
journal = {Journal of Food and Nutrition Sciences},
volume = {1},
number = {3},
pages = {23-32},
doi = {10.11648/j.jfns.20130103.11},
url = {https://doi.org/10.11648/j.jfns.20130103.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfns.20130103.11},
abstract = {The quality and quantity of protein are essential factors that determine nutritional significance of a protein. The aim of this study was to compare the effects of several animal and plant proteins on the progression of renal failure in rats. Ninety male rats were allocated into nine groups and were fed with a basal diet containing different protein sources for 12 weeks. Two groups comprised of a negative control group and a positive control group (with induced renal failure) fed on the basal diet. Rats in the remaining seven groups were fed using different diets containing 10% protein derived from fish, meat, chicken, egg, soybean, lentil, and white bean. Biological, biochemical and histological studies were done at the end of the study. Protein content was highest for the chicken extract (87.36%), followed by meat (85.67%), egg (78.85%), and fish (78.55%). Body weight gain increased as food intake decreased in all groups other than the positive control group, and the food efficiency ratio paralleled food intake. Rats fed the fish protein diet had lower blood urea nitrogen (28.0 mg/dL), uric acid (3.5mg/dL) levels compared with the other groups. There were no significant differences in creatinine levels between rats fed the animal protein (fish and meat) or the plant protein (soy and white bean) diets. Histological studies revealed no abnormal renal features in rats fed the fish or soybean protein diets. Therefore, the results of the study suggest that a diet containing fish protein may delay the progression of chronic renal failure relative to other protein diets.},
year = {2013}
}
TY - JOUR T1 - Effects of Dietary Protein Sources on the Progression of Renal Failure without Dialysis in Rats AU - Nadia Saleh Al-Amoudi Y1 - 2013/09/30 PY - 2013 N1 - https://doi.org/10.11648/j.jfns.20130103.11 DO - 10.11648/j.jfns.20130103.11 T2 - Journal of Food and Nutrition Sciences JF - Journal of Food and Nutrition Sciences JO - Journal of Food and Nutrition Sciences SP - 23 EP - 32 PB - Science Publishing Group SN - 2330-7293 UR - https://doi.org/10.11648/j.jfns.20130103.11 AB - The quality and quantity of protein are essential factors that determine nutritional significance of a protein. The aim of this study was to compare the effects of several animal and plant proteins on the progression of renal failure in rats. Ninety male rats were allocated into nine groups and were fed with a basal diet containing different protein sources for 12 weeks. Two groups comprised of a negative control group and a positive control group (with induced renal failure) fed on the basal diet. Rats in the remaining seven groups were fed using different diets containing 10% protein derived from fish, meat, chicken, egg, soybean, lentil, and white bean. Biological, biochemical and histological studies were done at the end of the study. Protein content was highest for the chicken extract (87.36%), followed by meat (85.67%), egg (78.85%), and fish (78.55%). Body weight gain increased as food intake decreased in all groups other than the positive control group, and the food efficiency ratio paralleled food intake. Rats fed the fish protein diet had lower blood urea nitrogen (28.0 mg/dL), uric acid (3.5mg/dL) levels compared with the other groups. There were no significant differences in creatinine levels between rats fed the animal protein (fish and meat) or the plant protein (soy and white bean) diets. Histological studies revealed no abnormal renal features in rats fed the fish or soybean protein diets. Therefore, the results of the study suggest that a diet containing fish protein may delay the progression of chronic renal failure relative to other protein diets. VL - 1 IS - 3 ER -
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