Introduction: Blood types are most often incriminated in susceptibility to COVID-19. Blood group O subjects are reportedly less susceptible to COVID-19. However, these reports are mainly from countries with high infection rates. The overall objective of this study was to investigate the association between the risk of COVID-19 infection, its severity, and ABO-RHD blood groups at the Training Hospitals of Bouake and Cocody (Ivory Coast). Material and methods: This was a prospective study that lasted four months. All patients with COVID-19 at the time of the study and followed at the Training Hospitals of Bouake and Cocody, hospitalized in the COVID-19 centers or in home confinement, were included. T lymphocyte subpopulations were counted on the BD FACS Calibur flow cytometer after labeling. ABO and RHD blood typing was performed in all patients. Results: Of the 76 patients collected, 78.9% were homebound, 18.4% in hospital and 2.6% in the ICU. The mean age was 41.92 ± 15.13 years with a male predominance. The majority of hospitalized patients were significantly of blood group A (p=0.020). CD4 and CD8 T lymphopenia were significantly more frequent in patients with blood group A than in those with blood groups B, AB and O. Conclusion: The impact of blood group on the severity of the disease would exist. Our study showed that blood group A subjects were more likely to have COVID-19. In addition, a statistically significant association between blood type A and CD4 and CD8 T lymphopenia was found. These results should be confirmed by studies based on larger patient samples.
| Published in | International Journal of Immunology (Volume 11, Issue 1) |
| DOI | 10.11648/j.iji.20231101.11 |
| Page(s) | 1-5 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2023. Published by Science Publishing Group |
Lymphopenia, CD4, CD8, COVID-19, ABO-RHD Blood Groups
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APA Style
Adou Adjoumanvoule Honore, Siransy Kouabla Liliane, Memel Lasme Roselle Charline, Yeboah Oppong Richard, Goran-Kouacou Amah Patricia, et al. (2023). Association Between ABO-RHD Blood Groups and COVID-19: A Preliminary Study of 76 Cases. International Journal of Immunology, 11(1), 1-5. https://doi.org/10.11648/j.iji.20231101.11
ACS Style
Adou Adjoumanvoule Honore; Siransy Kouabla Liliane; Memel Lasme Roselle Charline; Yeboah Oppong Richard; Goran-Kouacou Amah Patricia, et al. Association Between ABO-RHD Blood Groups and COVID-19: A Preliminary Study of 76 Cases. Int. J. Immunol. 2023, 11(1), 1-5. doi: 10.11648/j.iji.20231101.11
AMA Style
Adou Adjoumanvoule Honore, Siransy Kouabla Liliane, Memel Lasme Roselle Charline, Yeboah Oppong Richard, Goran-Kouacou Amah Patricia, et al. Association Between ABO-RHD Blood Groups and COVID-19: A Preliminary Study of 76 Cases. Int J Immunol. 2023;11(1):1-5. doi: 10.11648/j.iji.20231101.11
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Download@article{10.11648/j.iji.20231101.11,
author = {Adou Adjoumanvoule Honore and Siransy Kouabla Liliane and Memel Lasme Roselle Charline and Yeboah Oppong Richard and Goran-Kouacou Amah Patricia and Kone Djakaridja and Kadiane N’Dri Juliette and Assi Aya Ursule Aniela and Gnemagnon Mahi Eric Constant and Ouattara Awa and Oura Brou Doris and Moussa Sali and Koya Hebert Gautier and Seri Yida Jocelyne and Aba Yapo Thomas and Krah Ouffoue},
title = {Association Between ABO-RHD Blood Groups and COVID-19: A Preliminary Study of 76 Cases},
journal = {International Journal of Immunology},
volume = {11},
number = {1},
pages = {1-5},
doi = {10.11648/j.iji.20231101.11},
url = {https://doi.org/10.11648/j.iji.20231101.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20231101.11},
abstract = {Introduction: Blood types are most often incriminated in susceptibility to COVID-19. Blood group O subjects are reportedly less susceptible to COVID-19. However, these reports are mainly from countries with high infection rates. The overall objective of this study was to investigate the association between the risk of COVID-19 infection, its severity, and ABO-RHD blood groups at the Training Hospitals of Bouake and Cocody (Ivory Coast). Material and methods: This was a prospective study that lasted four months. All patients with COVID-19 at the time of the study and followed at the Training Hospitals of Bouake and Cocody, hospitalized in the COVID-19 centers or in home confinement, were included. T lymphocyte subpopulations were counted on the BD FACS Calibur flow cytometer after labeling. ABO and RHD blood typing was performed in all patients. Results: Of the 76 patients collected, 78.9% were homebound, 18.4% in hospital and 2.6% in the ICU. The mean age was 41.92 ± 15.13 years with a male predominance. The majority of hospitalized patients were significantly of blood group A (p=0.020). CD4 and CD8 T lymphopenia were significantly more frequent in patients with blood group A than in those with blood groups B, AB and O. Conclusion: The impact of blood group on the severity of the disease would exist. Our study showed that blood group A subjects were more likely to have COVID-19. In addition, a statistically significant association between blood type A and CD4 and CD8 T lymphopenia was found. These results should be confirmed by studies based on larger patient samples.},
year = {2023}
}
TY - JOUR T1 - Association Between ABO-RHD Blood Groups and COVID-19: A Preliminary Study of 76 Cases AU - Adou Adjoumanvoule Honore AU - Siransy Kouabla Liliane AU - Memel Lasme Roselle Charline AU - Yeboah Oppong Richard AU - Goran-Kouacou Amah Patricia AU - Kone Djakaridja AU - Kadiane N’Dri Juliette AU - Assi Aya Ursule Aniela AU - Gnemagnon Mahi Eric Constant AU - Ouattara Awa AU - Oura Brou Doris AU - Moussa Sali AU - Koya Hebert Gautier AU - Seri Yida Jocelyne AU - Aba Yapo Thomas AU - Krah Ouffoue Y1 - 2023/05/10 PY - 2023 N1 - https://doi.org/10.11648/j.iji.20231101.11 DO - 10.11648/j.iji.20231101.11 T2 - International Journal of Immunology JF - International Journal of Immunology JO - International Journal of Immunology SP - 1 EP - 5 PB - Science Publishing Group SN - 2329-1753 UR - https://doi.org/10.11648/j.iji.20231101.11 AB - Introduction: Blood types are most often incriminated in susceptibility to COVID-19. Blood group O subjects are reportedly less susceptible to COVID-19. However, these reports are mainly from countries with high infection rates. The overall objective of this study was to investigate the association between the risk of COVID-19 infection, its severity, and ABO-RHD blood groups at the Training Hospitals of Bouake and Cocody (Ivory Coast). Material and methods: This was a prospective study that lasted four months. All patients with COVID-19 at the time of the study and followed at the Training Hospitals of Bouake and Cocody, hospitalized in the COVID-19 centers or in home confinement, were included. T lymphocyte subpopulations were counted on the BD FACS Calibur flow cytometer after labeling. ABO and RHD blood typing was performed in all patients. Results: Of the 76 patients collected, 78.9% were homebound, 18.4% in hospital and 2.6% in the ICU. The mean age was 41.92 ± 15.13 years with a male predominance. The majority of hospitalized patients were significantly of blood group A (p=0.020). CD4 and CD8 T lymphopenia were significantly more frequent in patients with blood group A than in those with blood groups B, AB and O. Conclusion: The impact of blood group on the severity of the disease would exist. Our study showed that blood group A subjects were more likely to have COVID-19. In addition, a statistically significant association between blood type A and CD4 and CD8 T lymphopenia was found. These results should be confirmed by studies based on larger patient samples. VL - 11 IS - 1 ER -
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