Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy

Taha Luqman Bilgrami; Hira Saleem

doi:doi:10.11648/j.iji.20221001.13

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Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy

Taha Luqman Bilgrami, Hira Saleem

Published in International Journal of Immunology (Volume 10, Issue 1)

Received: 23 April 2022 Accepted: 20 May 2022 Published: 31 May 2022

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Abstract

Eosinophilia, a peripheral blood with eosinophil count of more than 450 cells per microliter has been linked to allergies, medication responses, among others. However, the reduction in eosinophil levels has been particularly found to be having linkage with SARS-CoV-2 infection. This study aims at comparing COVID-19 patients' peripheral blood eosinophil levels to seasonal allergy patients' eosinophil counts to determine whether there is a link between eosinophil numbers and COVID-19 disease severity. Data was obtained from the review of the electronic medical records of 300 confirmed COVID-19 patients, alongside their clinical features were obtained. Data collected was then subjected to retrospective cohort analysis. Eosinopenia was found in 73.7 percent, 86.7 percent, and 94.3 percent of patients in the mild, moderate, and severe categories, respectively (p value 0.002). When compared to patients with moderate and severe illnesses, patients with critical disease had significantly lower eosinophil levels. Results from this study shows that increase in COVID-19 severity is associated with a significant drop in peripheral eosinophil levels, and that eosinopenia was present in the majority of COVID-19 patients. Seasonal allergic rhinitis is indicated as a particularly good model for studying the potential pathogenic effects of eosinophils and eosinophilic inflammation.

Published in	International Journal of Immunology (Volume 10, Issue 1)
DOI	10.11648/j.iji.20221001.13
Page(s)	11-14
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Eosinophil Levels, COVID-19, Immunity, Allergy

References

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APA Style

Taha Luqman Bilgrami, Hira Saleem. (2022). Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy. International Journal of Immunology, 10(1), 11-14. https://doi.org/10.11648/j.iji.20221001.13

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ACS Style

Taha Luqman Bilgrami; Hira Saleem. Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy. Int. J. Immunol. 2022, 10(1), 11-14. doi: 10.11648/j.iji.20221001.13

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AMA Style

Taha Luqman Bilgrami, Hira Saleem. Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy. Int J Immunol. 2022;10(1):11-14. doi: 10.11648/j.iji.20221001.13

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@article{10.11648/j.iji.20221001.13,
  author = {Taha Luqman Bilgrami and Hira Saleem},
  title = {Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy},
  journal = {International Journal of Immunology},
  volume = {10},
  number = {1},
  pages = {11-14},
  doi = {10.11648/j.iji.20221001.13},
  url = {https://doi.org/10.11648/j.iji.20221001.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20221001.13},
  abstract = {Eosinophilia, a peripheral blood with eosinophil count of more than 450 cells per microliter has been linked to allergies, medication responses, among others. However, the reduction in eosinophil levels has been particularly found to be having linkage with SARS-CoV-2 infection. This study aims at comparing COVID-19 patients' peripheral blood eosinophil levels to seasonal allergy patients' eosinophil counts to determine whether there is a link between eosinophil numbers and COVID-19 disease severity. Data was obtained from the review of the electronic medical records of 300 confirmed COVID-19 patients, alongside their clinical features were obtained. Data collected was then subjected to retrospective cohort analysis. Eosinopenia was found in 73.7 percent, 86.7 percent, and 94.3 percent of patients in the mild, moderate, and severe categories, respectively (p value 0.002). When compared to patients with moderate and severe illnesses, patients with critical disease had significantly lower eosinophil levels. Results from this study shows that increase in COVID-19 severity is associated with a significant drop in peripheral eosinophil levels, and that eosinopenia was present in the majority of COVID-19 patients. Seasonal allergic rhinitis is indicated as a particularly good model for studying the potential pathogenic effects of eosinophils and eosinophilic inflammation.},
 year = {2022}
}

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TY  - JOUR
T1  - Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy
AU  - Taha Luqman Bilgrami
AU  - Hira Saleem
Y1  - 2022/05/31
PY  - 2022
N1  - https://doi.org/10.11648/j.iji.20221001.13
DO  - 10.11648/j.iji.20221001.13
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 11
EP  - 14
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20221001.13
AB  - Eosinophilia, a peripheral blood with eosinophil count of more than 450 cells per microliter has been linked to allergies, medication responses, among others. However, the reduction in eosinophil levels has been particularly found to be having linkage with SARS-CoV-2 infection. This study aims at comparing COVID-19 patients' peripheral blood eosinophil levels to seasonal allergy patients' eosinophil counts to determine whether there is a link between eosinophil numbers and COVID-19 disease severity. Data was obtained from the review of the electronic medical records of 300 confirmed COVID-19 patients, alongside their clinical features were obtained. Data collected was then subjected to retrospective cohort analysis. Eosinopenia was found in 73.7 percent, 86.7 percent, and 94.3 percent of patients in the mild, moderate, and severe categories, respectively (p value 0.002). When compared to patients with moderate and severe illnesses, patients with critical disease had significantly lower eosinophil levels. Results from this study shows that increase in COVID-19 severity is associated with a significant drop in peripheral eosinophil levels, and that eosinopenia was present in the majority of COVID-19 patients. Seasonal allergic rhinitis is indicated as a particularly good model for studying the potential pathogenic effects of eosinophils and eosinophilic inflammation.
VL  - 10
IS  - 1
ER  -

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Author Information

Taha Luqman Bilgrami

Department of Internal Medicine, University of Debrecen, Debrecen, Hungary
Hira Saleem

Department of Internal Medicine, Bahria University, Karachi, Pakistan

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APA Style

Taha Luqman Bilgrami, Hira Saleem. (2022). Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy. International Journal of Immunology, 10(1), 11-14. https://doi.org/10.11648/j.iji.20221001.13

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ACS Style

Taha Luqman Bilgrami; Hira Saleem. Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy. Int. J. Immunol. 2022, 10(1), 11-14. doi: 10.11648/j.iji.20221001.13

Copy | Download

AMA Style

Taha Luqman Bilgrami, Hira Saleem. Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy. Int J Immunol. 2022;10(1):11-14. doi: 10.11648/j.iji.20221001.13

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@article{10.11648/j.iji.20221001.13,
  author = {Taha Luqman Bilgrami and Hira Saleem},
  title = {Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy},
  journal = {International Journal of Immunology},
  volume = {10},
  number = {1},
  pages = {11-14},
  doi = {10.11648/j.iji.20221001.13},
  url = {https://doi.org/10.11648/j.iji.20221001.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.iji.20221001.13},
  abstract = {Eosinophilia, a peripheral blood with eosinophil count of more than 450 cells per microliter has been linked to allergies, medication responses, among others. However, the reduction in eosinophil levels has been particularly found to be having linkage with SARS-CoV-2 infection. This study aims at comparing COVID-19 patients' peripheral blood eosinophil levels to seasonal allergy patients' eosinophil counts to determine whether there is a link between eosinophil numbers and COVID-19 disease severity. Data was obtained from the review of the electronic medical records of 300 confirmed COVID-19 patients, alongside their clinical features were obtained. Data collected was then subjected to retrospective cohort analysis. Eosinopenia was found in 73.7 percent, 86.7 percent, and 94.3 percent of patients in the mild, moderate, and severe categories, respectively (p value 0.002). When compared to patients with moderate and severe illnesses, patients with critical disease had significantly lower eosinophil levels. Results from this study shows that increase in COVID-19 severity is associated with a significant drop in peripheral eosinophil levels, and that eosinopenia was present in the majority of COVID-19 patients. Seasonal allergic rhinitis is indicated as a particularly good model for studying the potential pathogenic effects of eosinophils and eosinophilic inflammation.},
 year = {2022}
}

Copy | Download

TY  - JOUR
T1  - Eosinophil Levels in Blood of COVID-19 Patient’s VS Seasonal Allergy
AU  - Taha Luqman Bilgrami
AU  - Hira Saleem
Y1  - 2022/05/31
PY  - 2022
N1  - https://doi.org/10.11648/j.iji.20221001.13
DO  - 10.11648/j.iji.20221001.13
T2  - International Journal of Immunology
JF  - International Journal of Immunology
JO  - International Journal of Immunology
SP  - 11
EP  - 14
PB  - Science Publishing Group
SN  - 2329-1753
UR  - https://doi.org/10.11648/j.iji.20221001.13
AB  - Eosinophilia, a peripheral blood with eosinophil count of more than 450 cells per microliter has been linked to allergies, medication responses, among others. However, the reduction in eosinophil levels has been particularly found to be having linkage with SARS-CoV-2 infection. This study aims at comparing COVID-19 patients' peripheral blood eosinophil levels to seasonal allergy patients' eosinophil counts to determine whether there is a link between eosinophil numbers and COVID-19 disease severity. Data was obtained from the review of the electronic medical records of 300 confirmed COVID-19 patients, alongside their clinical features were obtained. Data collected was then subjected to retrospective cohort analysis. Eosinopenia was found in 73.7 percent, 86.7 percent, and 94.3 percent of patients in the mild, moderate, and severe categories, respectively (p value 0.002). When compared to patients with moderate and severe illnesses, patients with critical disease had significantly lower eosinophil levels. Results from this study shows that increase in COVID-19 severity is associated with a significant drop in peripheral eosinophil levels, and that eosinopenia was present in the majority of COVID-19 patients. Seasonal allergic rhinitis is indicated as a particularly good model for studying the potential pathogenic effects of eosinophils and eosinophilic inflammation.
VL  - 10
IS  - 1
ER  -

Copy | Download