Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia

Fumio Bessho; Masako Tanimura

doi:doi:10.11648/j.ejpm.20200805.11

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Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia

Fumio Bessho, Masako Tanimura

Published in European Journal of Preventive Medicine (Volume 8, Issue 5)

Received: 28 August 2020 Accepted: 11 September 2020 Published: 23 September 2020

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Abstract

We herein determined the effects of parental smoking on occurrence of childhood acute leukemia using the large volume of data accumulated in the Japan Children's Cancer Registry. Information on the smoking statuses of fathers was available for 4,802 acute leukemia cases diagnosed between 1985 and 2006 and that of mothers was available for 5,536 cases diagnosed between 1978 and 2006. We compared the smoking rates of parents whose children were diagnosed with leukemia with a control group of parents whose children were diagnosed with benign tumors or cancer-related diseases. The smoking rate of fathers was significantly larger than the control. The odds ratios were 1.284 for 1-9 cigarettes/day (c/d) before conception (p=0.127), 1.265 for 10-19 c/d (p=0.029), and 1.345 for more than 20 c/d (p=0.000). A logistic regression analysis controlling for sex, birth weight, paternal age at birth, and maternal smoking showed that the smoking rate of fathers whose children had acute leukemia was still significantly higher (OR 1.012, p=0.004). The difference of the smoking rate between mothers whose children had acute leukemia and the control mothers was not significant (OR 1.161, p=0.447).

Published in	European Journal of Preventive Medicine (Volume 8, Issue 5)
DOI	10.11648/j.ejpm.20200805.11
Page(s)	61-65
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Childhood Acute Leukemia, Parental Smoking, Sperm, Fetus

References

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APA Style

Fumio Bessho, Masako Tanimura. (2020). Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia. European Journal of Preventive Medicine, 8(5), 61-65. https://doi.org/10.11648/j.ejpm.20200805.11

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ACS Style

Fumio Bessho; Masako Tanimura. Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia. Eur. J. Prev. Med. 2020, 8(5), 61-65. doi: 10.11648/j.ejpm.20200805.11

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AMA Style

Fumio Bessho, Masako Tanimura. Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia. Eur J Prev Med. 2020;8(5):61-65. doi: 10.11648/j.ejpm.20200805.11

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@article{10.11648/j.ejpm.20200805.11,
  author = {Fumio Bessho and Masako Tanimura},
  title = {Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia},
  journal = {European Journal of Preventive Medicine},
  volume = {8},
  number = {5},
  pages = {61-65},
  doi = {10.11648/j.ejpm.20200805.11},
  url = {https://doi.org/10.11648/j.ejpm.20200805.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20200805.11},
  abstract = {We herein determined the effects of parental smoking on occurrence of childhood acute leukemia using the large volume of data accumulated in the Japan Children's Cancer Registry. Information on the smoking statuses of fathers was available for 4,802 acute leukemia cases diagnosed between 1985 and 2006 and that of mothers was available for 5,536 cases diagnosed between 1978 and 2006. We compared the smoking rates of parents whose children were diagnosed with leukemia with a control group of parents whose children were diagnosed with benign tumors or cancer-related diseases. The smoking rate of fathers was significantly larger than the control. The odds ratios were 1.284 for 1-9 cigarettes/day (c/d) before conception (p=0.127), 1.265 for 10-19 c/d (p=0.029), and 1.345 for more than 20 c/d (p=0.000). A logistic regression analysis controlling for sex, birth weight, paternal age at birth, and maternal smoking showed that the smoking rate of fathers whose children had acute leukemia was still significantly higher (OR 1.012, p=0.004). The difference of the smoking rate between mothers whose children had acute leukemia and the control mothers was not significant (OR 1.161, p=0.447).},
 year = {2020}
}

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TY  - JOUR
T1  - Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia
AU  - Fumio Bessho
AU  - Masako Tanimura
Y1  - 2020/09/23
PY  - 2020
N1  - https://doi.org/10.11648/j.ejpm.20200805.11
DO  - 10.11648/j.ejpm.20200805.11
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 61
EP  - 65
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20200805.11
AB  - We herein determined the effects of parental smoking on occurrence of childhood acute leukemia using the large volume of data accumulated in the Japan Children's Cancer Registry. Information on the smoking statuses of fathers was available for 4,802 acute leukemia cases diagnosed between 1985 and 2006 and that of mothers was available for 5,536 cases diagnosed between 1978 and 2006. We compared the smoking rates of parents whose children were diagnosed with leukemia with a control group of parents whose children were diagnosed with benign tumors or cancer-related diseases. The smoking rate of fathers was significantly larger than the control. The odds ratios were 1.284 for 1-9 cigarettes/day (c/d) before conception (p=0.127), 1.265 for 10-19 c/d (p=0.029), and 1.345 for more than 20 c/d (p=0.000). A logistic regression analysis controlling for sex, birth weight, paternal age at birth, and maternal smoking showed that the smoking rate of fathers whose children had acute leukemia was still significantly higher (OR 1.012, p=0.004). The difference of the smoking rate between mothers whose children had acute leukemia and the control mothers was not significant (OR 1.161, p=0.447).
VL  - 8
IS  - 5
ER  -

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Author Information

Fumio Bessho

Department of Education of General Medicine, Faculty of Health Sciences, Nihon Institute of Medical Science, Saitama, Japan
Masako Tanimura

Department of Pediatrics, Kyorin University School of Medicine, Tokyo, Japan

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APA Style

Fumio Bessho, Masako Tanimura. (2020). Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia. European Journal of Preventive Medicine, 8(5), 61-65. https://doi.org/10.11648/j.ejpm.20200805.11

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ACS Style

Fumio Bessho; Masako Tanimura. Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia. Eur. J. Prev. Med. 2020, 8(5), 61-65. doi: 10.11648/j.ejpm.20200805.11

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AMA Style

Fumio Bessho, Masako Tanimura. Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia. Eur J Prev Med. 2020;8(5):61-65. doi: 10.11648/j.ejpm.20200805.11

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@article{10.11648/j.ejpm.20200805.11,
  author = {Fumio Bessho and Masako Tanimura},
  title = {Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia},
  journal = {European Journal of Preventive Medicine},
  volume = {8},
  number = {5},
  pages = {61-65},
  doi = {10.11648/j.ejpm.20200805.11},
  url = {https://doi.org/10.11648/j.ejpm.20200805.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ejpm.20200805.11},
  abstract = {We herein determined the effects of parental smoking on occurrence of childhood acute leukemia using the large volume of data accumulated in the Japan Children's Cancer Registry. Information on the smoking statuses of fathers was available for 4,802 acute leukemia cases diagnosed between 1985 and 2006 and that of mothers was available for 5,536 cases diagnosed between 1978 and 2006. We compared the smoking rates of parents whose children were diagnosed with leukemia with a control group of parents whose children were diagnosed with benign tumors or cancer-related diseases. The smoking rate of fathers was significantly larger than the control. The odds ratios were 1.284 for 1-9 cigarettes/day (c/d) before conception (p=0.127), 1.265 for 10-19 c/d (p=0.029), and 1.345 for more than 20 c/d (p=0.000). A logistic regression analysis controlling for sex, birth weight, paternal age at birth, and maternal smoking showed that the smoking rate of fathers whose children had acute leukemia was still significantly higher (OR 1.012, p=0.004). The difference of the smoking rate between mothers whose children had acute leukemia and the control mothers was not significant (OR 1.161, p=0.447).},
 year = {2020}
}

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TY  - JOUR
T1  - Effects of Parental Smoking on Occurrence of Childhood Acute Leukemia
AU  - Fumio Bessho
AU  - Masako Tanimura
Y1  - 2020/09/23
PY  - 2020
N1  - https://doi.org/10.11648/j.ejpm.20200805.11
DO  - 10.11648/j.ejpm.20200805.11
T2  - European Journal of Preventive Medicine
JF  - European Journal of Preventive Medicine
JO  - European Journal of Preventive Medicine
SP  - 61
EP  - 65
PB  - Science Publishing Group
SN  - 2330-8230
UR  - https://doi.org/10.11648/j.ejpm.20200805.11
AB  - We herein determined the effects of parental smoking on occurrence of childhood acute leukemia using the large volume of data accumulated in the Japan Children's Cancer Registry. Information on the smoking statuses of fathers was available for 4,802 acute leukemia cases diagnosed between 1985 and 2006 and that of mothers was available for 5,536 cases diagnosed between 1978 and 2006. We compared the smoking rates of parents whose children were diagnosed with leukemia with a control group of parents whose children were diagnosed with benign tumors or cancer-related diseases. The smoking rate of fathers was significantly larger than the control. The odds ratios were 1.284 for 1-9 cigarettes/day (c/d) before conception (p=0.127), 1.265 for 10-19 c/d (p=0.029), and 1.345 for more than 20 c/d (p=0.000). A logistic regression analysis controlling for sex, birth weight, paternal age at birth, and maternal smoking showed that the smoking rate of fathers whose children had acute leukemia was still significantly higher (OR 1.012, p=0.004). The difference of the smoking rate between mothers whose children had acute leukemia and the control mothers was not significant (OR 1.161, p=0.447).
VL  - 8
IS  - 5
ER  -

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