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Prevalence of ESBL, AmpC and Carbapenemase among Gram Negative Bacilli Isolated from Clinical Specimens

Received: 12 March 2014     Accepted: 9 April 2014     Published: 20 April 2014
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Abstract

Background: Antimicrobial resistance is a growing threat worldwide. The predominant mechanisms for resistance to the β-lactam antibiotics in gram negative bacilli is the production of β-lactamases. Aim: To determine the prevalence of ESBL, AmpC and carbapenemase production among GNB isolated from various clinical samples. Materials and Methods: A total of 378 GNB isolated were identified and processed for the detection of ESBL, AmpC and Carbapemase production using various methods. Results: Out 378 GNB 197 (52.12%) showed the presence of one or more β-lactamases and 181 (47.88%) were negative. 33.86%, 14.24% and 18.25% showed the presence of ESBL, AmpC and Carbapenemase among the 378 GNB studied. Conclusion: This study highlights the prevalence of ESBL, AmpC and Carbepenemase producing GNB in a rural tertiary care teaching hospital

Published in American Journal of Life Sciences (Volume 2, Issue 2)
DOI 10.11648/j.ajls.20140202.17
Page(s) 76-81
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

ESBL, AmpC, Carbapenemase, Gram Negative Bacilli

References
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[9] Singhal S, Mathur T, Khan S, Upadhyay DJ, Chugh S, Gaind, Rattan A. Evaluation of Methods for AmpC Beta-Lactamase in gram negative clinical isolates from tertiary care hospitals. Indian J Med Microbiol. 2005;23(2): 120-124.
[10] Nirav P, Pandya, Sweta B, Prajapati, Sanjay J, Mehta et al. Evalution of various methods for detection of metallo-? -lactamase (MBL) production in Gram negative bacilli.Int J Biol Med Res 2011;2(3):775-777 .
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  • APA Style

    Vijaya Doddaiah, Dhanalakshmi Anjaneya. (2014). Prevalence of ESBL, AmpC and Carbapenemase among Gram Negative Bacilli Isolated from Clinical Specimens. American Journal of Life Sciences, 2(2), 76-81. https://doi.org/10.11648/j.ajls.20140202.17

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    ACS Style

    Vijaya Doddaiah; Dhanalakshmi Anjaneya. Prevalence of ESBL, AmpC and Carbapenemase among Gram Negative Bacilli Isolated from Clinical Specimens. Am. J. Life Sci. 2014, 2(2), 76-81. doi: 10.11648/j.ajls.20140202.17

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    AMA Style

    Vijaya Doddaiah, Dhanalakshmi Anjaneya. Prevalence of ESBL, AmpC and Carbapenemase among Gram Negative Bacilli Isolated from Clinical Specimens. Am J Life Sci. 2014;2(2):76-81. doi: 10.11648/j.ajls.20140202.17

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  • @article{10.11648/j.ajls.20140202.17,
      author = {Vijaya Doddaiah and Dhanalakshmi Anjaneya},
      title = {Prevalence of ESBL, AmpC and Carbapenemase among Gram Negative Bacilli Isolated from Clinical Specimens},
      journal = {American Journal of Life Sciences},
      volume = {2},
      number = {2},
      pages = {76-81},
      doi = {10.11648/j.ajls.20140202.17},
      url = {https://doi.org/10.11648/j.ajls.20140202.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajls.20140202.17},
      abstract = {Background: Antimicrobial resistance is a growing threat worldwide. The predominant mechanisms for resistance to the β-lactam antibiotics in gram negative bacilli is the production of β-lactamases. Aim: To determine the prevalence of ESBL, AmpC and carbapenemase production among GNB isolated from various clinical samples. Materials and Methods: A total of 378 GNB isolated were identified and processed for the detection of ESBL, AmpC and Carbapemase production using various methods. Results: Out 378 GNB 197 (52.12%) showed the presence of one or more β-lactamases and 181 (47.88%) were negative. 33.86%, 14.24% and 18.25% showed the presence of ESBL, AmpC and Carbapenemase among the 378 GNB studied. Conclusion: This study highlights the prevalence of ESBL, AmpC and Carbepenemase producing GNB in a rural tertiary care teaching hospital},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Prevalence of ESBL, AmpC and Carbapenemase among Gram Negative Bacilli Isolated from Clinical Specimens
    AU  - Vijaya Doddaiah
    AU  - Dhanalakshmi Anjaneya
    Y1  - 2014/04/20
    PY  - 2014
    N1  - https://doi.org/10.11648/j.ajls.20140202.17
    DO  - 10.11648/j.ajls.20140202.17
    T2  - American Journal of Life Sciences
    JF  - American Journal of Life Sciences
    JO  - American Journal of Life Sciences
    SP  - 76
    EP  - 81
    PB  - Science Publishing Group
    SN  - 2328-5737
    UR  - https://doi.org/10.11648/j.ajls.20140202.17
    AB  - Background: Antimicrobial resistance is a growing threat worldwide. The predominant mechanisms for resistance to the β-lactam antibiotics in gram negative bacilli is the production of β-lactamases. Aim: To determine the prevalence of ESBL, AmpC and carbapenemase production among GNB isolated from various clinical samples. Materials and Methods: A total of 378 GNB isolated were identified and processed for the detection of ESBL, AmpC and Carbapemase production using various methods. Results: Out 378 GNB 197 (52.12%) showed the presence of one or more β-lactamases and 181 (47.88%) were negative. 33.86%, 14.24% and 18.25% showed the presence of ESBL, AmpC and Carbapenemase among the 378 GNB studied. Conclusion: This study highlights the prevalence of ESBL, AmpC and Carbepenemase producing GNB in a rural tertiary care teaching hospital
    VL  - 2
    IS  - 2
    ER  - 

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Author Information
  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

  • Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, B. G. Nagara, Karnataka, India

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