Objective: This study investigated the changes in the anterior pituitary hormones of patients who were admitted to an emergency service and diagnosed with acute meningitis. Methods: A total of 21 patients who were admitted to an emergency service between 01 January and 31 October 2012, and diagnosed with meningitis, were included. Blood samples were collected from the patients within an initial 24 hours of admission and at month 6, in order to measure thyroid-stimulating hormone (TSH), growth hormone (GH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and adrenocorticotropic hormone (ACTH) levels. The results were analyzed using SSPS-18 software. Results: Of the patients, 47.6% were male, and 52.4% were female. At month 6, TSH, LH, and ACTH levels were higher than those measured on admission. This difference was meaningful for TSH, but insignificant for LH and ACTH. At month 6, mean GH, FSH, and PRL levels were lower than admission levels. At the time of admission, FSH was at lower than normal levels in seven patients, LH was lower in six patients, TSH was lower in four patients, GH was lower in four patients, and ACTH in was lower in three patients. At month 6, FSH was lower in five patients, LH was lower in four patients, TSH was lower in one patient, GH was lower in six patients, and ACTH was lower in five patients. Conclusion: The differences between hormone levels at admission and at month 6 show that meningitis causes changes in anterior pituitary hormones.
| Published in | American Journal of Health Research (Volume 1, Issue 3) |
| DOI | 10.11648/j.ajhr.20130103.11 |
| Page(s) | 36-41 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Meningitis, Anterior Pituitary Function, Changes in Anterior Pituitary Hormones
| [1] | Schaefer S, Hypothalamic-pituitary insufficiency following infectious diseases of the central nervous system. Eur J Endocrinol 2008;158:3–9. |
| [2] | Schneider HJ, Kreitschmann-Andermahr I, Ghigo E, Stalla GK, Agha A Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review. JAMA 2007;298:1429–38. |
| [3] | Haslam RHA, Winternitz WW, Howieson J Selective hypopituitarism following tuberculous menigitis. Am J Dis Child 1969;118:903–8. |
| [4] | Tanriverdi F, Alp E, Demiraslan H, Dokmetas HS, Unluhizarci K, Doganay M, Casanueva FF, Kelestimur F Investigation of pituitary functions in patients with acute meningitis: a pilot study. J Endocrinol Invest 2008;31:489–491. |
| [5] | Tsiakalos A, Xynos ID, Sipsas NV, Kaltsas G Pituitary insufficiency after infectious meningitis: a prospective study. J Clin Endocrinol Metab 2010;95:3277–3281. |
| [6] | Tanriverdi F, De Bellis A, Teksahin H, Alp E, Bizzarro A, Sinisi AA, et al. Prospective investigation of pituitary functions in patients with acute infectious meningitis: is acute meningitis induced pituitary dysfunction associated with autoimmunity? Pituitary 2012;5:579–588. |
| [7] | Levy-Shraga Y, Gazit I, Modan-Moses D, Pinhas-Hamiel O. Pituitary function in children following infectious diseases of the central nervous system. Pituitary. 2013 Mar 8. DOI 10.1007/s11102-013-0476-2.[Epub ahead of print]. |
| [8] | Kupari M, Pelkonen R, Valtonen V. Post-encephalitic hypothalamic-pititary insufficiency. Acta Endocrinol 1980; 94: 433-438. |
| [9] | Lichtenstein MJ, Tilley WS, Sandler MP. The syndrome of hypothalamic hypopituitarism complicating viral meningoencephalitis. J Endocrinol Invest 1982; 5: 111-115. |
| [10] | Ickenstein GW, Klotz JM, Langohr HD. Virus encephalitis with symptomatic Parkinson syndrome, diabetes insipidus and panhypopituitarism. Fortschr Neurol Psychiatr 1999;67:476–481. |
| [11] | Hagg E, Astrom L, Steen L. Persistent hypothalamic–pituitary insufficiency following acute meningoencephalitis. Acta Medica Scandinavica 1978;203:231–235. |
| [12] | Jew K, Piziak V, Gilliland PF & Hurley DL. Meningoencephalitis complicated by pituitary insufficiency and a spontaneously resolving suprasellar mass. Neurosurgery 1984 14 567–569. |
| [13] | Vesely DL, Mastrandrea P, Samson C, Argyelan G & Charvit S. Post-herpes encephalitic anterior pituitary insufficiency with hypothermia and hypotension. American Journal of the Medical Sciences 2000;320:273–277. |
| [14] | Katsuno M, Yamazaki M, Tahara S, Murai Y, Teramono A, Sano N. Spontaneous remission of acromegaly after meningitis: a case report. No To Shinkei 2003;55:967-971. |
| [15] | Lynch C, Fish M. Bacterial meningitis resulting in visual impairment and panhypopituitarism. Br J Hosp Med 2007;68:272. |
APA Style
Suat Zengin, Behcet Al, Mehmet Dogan, Basri Can, Mustafa Bogan, et al. (2013). The Effects of Meningitis on Anterior Pituitary Functions. American Journal of Health Research, 1(3), 36-41. https://doi.org/10.11648/j.ajhr.20130103.11
ACS Style
Suat Zengin; Behcet Al; Mehmet Dogan; Basri Can; Mustafa Bogan, et al. The Effects of Meningitis on Anterior Pituitary Functions. Am. J. Health Res. 2013, 1(3), 36-41. doi: 10.11648/j.ajhr.20130103.11
AMA Style
Suat Zengin, Behcet Al, Mehmet Dogan, Basri Can, Mustafa Bogan, et al. The Effects of Meningitis on Anterior Pituitary Functions. Am J Health Res. 2013;1(3):36-41. doi: 10.11648/j.ajhr.20130103.11
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Download@article{10.11648/j.ajhr.20130103.11,
author = {Suat Zengin and Behcet Al and Mehmet Dogan and Basri Can and Mustafa Bogan and Cuma Yildirim},
title = {The Effects of Meningitis on Anterior Pituitary Functions},
journal = {American Journal of Health Research},
volume = {1},
number = {3},
pages = {36-41},
doi = {10.11648/j.ajhr.20130103.11},
url = {https://doi.org/10.11648/j.ajhr.20130103.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhr.20130103.11},
abstract = {Objective: This study investigated the changes in the anterior pituitary hormones of patients who were admitted to an emergency service and diagnosed with acute meningitis. Methods: A total of 21 patients who were admitted to an emergency service between 01 January and 31 October 2012, and diagnosed with meningitis, were included. Blood samples were collected from the patients within an initial 24 hours of admission and at month 6, in order to measure thyroid-stimulating hormone (TSH), growth hormone (GH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and adrenocorticotropic hormone (ACTH) levels. The results were analyzed using SSPS-18 software. Results: Of the patients, 47.6% were male, and 52.4% were female. At month 6, TSH, LH, and ACTH levels were higher than those measured on admission. This difference was meaningful for TSH, but insignificant for LH and ACTH. At month 6, mean GH, FSH, and PRL levels were lower than admission levels. At the time of admission, FSH was at lower than normal levels in seven patients, LH was lower in six patients, TSH was lower in four patients, GH was lower in four patients, and ACTH in was lower in three patients. At month 6, FSH was lower in five patients, LH was lower in four patients, TSH was lower in one patient, GH was lower in six patients, and ACTH was lower in five patients. Conclusion: The differences between hormone levels at admission and at month 6 show that meningitis causes changes in anterior pituitary hormones.},
year = {2013}
}
TY - JOUR T1 - The Effects of Meningitis on Anterior Pituitary Functions AU - Suat Zengin AU - Behcet Al AU - Mehmet Dogan AU - Basri Can AU - Mustafa Bogan AU - Cuma Yildirim Y1 - 2013/10/20 PY - 2013 N1 - https://doi.org/10.11648/j.ajhr.20130103.11 DO - 10.11648/j.ajhr.20130103.11 T2 - American Journal of Health Research JF - American Journal of Health Research JO - American Journal of Health Research SP - 36 EP - 41 PB - Science Publishing Group SN - 2330-8796 UR - https://doi.org/10.11648/j.ajhr.20130103.11 AB - Objective: This study investigated the changes in the anterior pituitary hormones of patients who were admitted to an emergency service and diagnosed with acute meningitis. Methods: A total of 21 patients who were admitted to an emergency service between 01 January and 31 October 2012, and diagnosed with meningitis, were included. Blood samples were collected from the patients within an initial 24 hours of admission and at month 6, in order to measure thyroid-stimulating hormone (TSH), growth hormone (GH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), and adrenocorticotropic hormone (ACTH) levels. The results were analyzed using SSPS-18 software. Results: Of the patients, 47.6% were male, and 52.4% were female. At month 6, TSH, LH, and ACTH levels were higher than those measured on admission. This difference was meaningful for TSH, but insignificant for LH and ACTH. At month 6, mean GH, FSH, and PRL levels were lower than admission levels. At the time of admission, FSH was at lower than normal levels in seven patients, LH was lower in six patients, TSH was lower in four patients, GH was lower in four patients, and ACTH in was lower in three patients. At month 6, FSH was lower in five patients, LH was lower in four patients, TSH was lower in one patient, GH was lower in six patients, and ACTH was lower in five patients. Conclusion: The differences between hormone levels at admission and at month 6 show that meningitis causes changes in anterior pituitary hormones. VL - 1 IS - 3 ER -
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