Mansonella perstans and Plasmodium falciparum are among the most common human parasites in Sub-Saharan Africa. They pass through the bloodstream during their life in human host. This study aimed at determining the prevalence, determinants of co-infection with M. perstans and P. falciparum and their possible interaction mechanism. A cross-sectional study was conducted in the Akonolinga Health District among pupils. Each of them was screened for the presence of peripheral blood parasites stages using Giemsa-stained thick and thin blood films. Socio-demographic information was documented using a questionnaire forms. A total of 416 pupils aged 4-15 years (average: 9.17 ± 0.27) were recruited. The overall prevalence was 4.32% and 37.26% for M. perstans and P. falciparum respectively, and prevalence of co-infection was 1.92%. Mean parasite density was 508.7±310.3 (min: 430 - max: 1300) µF/ml for M. perstans and 5240.38±2037.42 (min: 857 – max: 10400) T/μl for P. falciparum. Risks of single infections (aOR = 0.46, P = 0.0264 for M. perstans and aOR = 0.64, P = 0.0432 for P. falciparum) and co-infection (aOR = 0.10, P = 0.0371) were lower for pupils living in urban area than those living in rural area. Parasitemia of both parasite species were similar in single and co-infection situations (P> 0.05). The interaction between these parasites could involve another mechanism than a competition for blood resources. This study outlined that M. perstans and P. falciparum are co-endemic in the Akonolinga health District. In order to guarantee future success in control and eradication of malaria, a bigger attention should be given to M. perstans or other filarial where it is co-endemic with P. falciparum.
| Published in | American Journal of Biomedical and Life Sciences (Volume 7, Issue 1) |
| DOI | 10.11648/j.ajbls.20190701.14 |
| Page(s) | 16-21 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Mansonella perstans, Plasmodium falciparum, Co-infection, Interaction, Akonolinga
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APA Style
Leopold Gustave Lehman, Martin Gael Oyono, Samuel Fosso, Charles Félix Bilong Bilong. (2019). Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon. American Journal of Biomedical and Life Sciences, 7(1), 16-21. https://doi.org/10.11648/j.ajbls.20190701.14
ACS Style
Leopold Gustave Lehman; Martin Gael Oyono; Samuel Fosso; Charles Félix Bilong Bilong. Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon. Am. J. Biomed. Life Sci. 2019, 7(1), 16-21. doi: 10.11648/j.ajbls.20190701.14
AMA Style
Leopold Gustave Lehman, Martin Gael Oyono, Samuel Fosso, Charles Félix Bilong Bilong. Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon. Am J Biomed Life Sci. 2019;7(1):16-21. doi: 10.11648/j.ajbls.20190701.14
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Download@article{10.11648/j.ajbls.20190701.14,
author = {Leopold Gustave Lehman and Martin Gael Oyono and Samuel Fosso and Charles Félix Bilong Bilong},
title = {Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon},
journal = {American Journal of Biomedical and Life Sciences},
volume = {7},
number = {1},
pages = {16-21},
doi = {10.11648/j.ajbls.20190701.14},
url = {https://doi.org/10.11648/j.ajbls.20190701.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20190701.14},
abstract = {Mansonella perstans and Plasmodium falciparum are among the most common human parasites in Sub-Saharan Africa. They pass through the bloodstream during their life in human host. This study aimed at determining the prevalence, determinants of co-infection with M. perstans and P. falciparum and their possible interaction mechanism. A cross-sectional study was conducted in the Akonolinga Health District among pupils. Each of them was screened for the presence of peripheral blood parasites stages using Giemsa-stained thick and thin blood films. Socio-demographic information was documented using a questionnaire forms. A total of 416 pupils aged 4-15 years (average: 9.17 ± 0.27) were recruited. The overall prevalence was 4.32% and 37.26% for M. perstans and P. falciparum respectively, and prevalence of co-infection was 1.92%. Mean parasite density was 508.7±310.3 (min: 430 - max: 1300) µF/ml for M. perstans and 5240.38±2037.42 (min: 857 – max: 10400) T/μl for P. falciparum. Risks of single infections (aOR = 0.46, P = 0.0264 for M. perstans and aOR = 0.64, P = 0.0432 for P. falciparum) and co-infection (aOR = 0.10, P = 0.0371) were lower for pupils living in urban area than those living in rural area. Parasitemia of both parasite species were similar in single and co-infection situations (P> 0.05). The interaction between these parasites could involve another mechanism than a competition for blood resources. This study outlined that M. perstans and P. falciparum are co-endemic in the Akonolinga health District. In order to guarantee future success in control and eradication of malaria, a bigger attention should be given to M. perstans or other filarial where it is co-endemic with P. falciparum.},
year = {2019}
}
TY - JOUR T1 - Mansonella perstans and Plasmodium falciparum Co-infection in the Akonolinga Health District, Centre Region, Cameroon AU - Leopold Gustave Lehman AU - Martin Gael Oyono AU - Samuel Fosso AU - Charles Félix Bilong Bilong Y1 - 2019/04/13 PY - 2019 N1 - https://doi.org/10.11648/j.ajbls.20190701.14 DO - 10.11648/j.ajbls.20190701.14 T2 - American Journal of Biomedical and Life Sciences JF - American Journal of Biomedical and Life Sciences JO - American Journal of Biomedical and Life Sciences SP - 16 EP - 21 PB - Science Publishing Group SN - 2330-880X UR - https://doi.org/10.11648/j.ajbls.20190701.14 AB - Mansonella perstans and Plasmodium falciparum are among the most common human parasites in Sub-Saharan Africa. They pass through the bloodstream during their life in human host. This study aimed at determining the prevalence, determinants of co-infection with M. perstans and P. falciparum and their possible interaction mechanism. A cross-sectional study was conducted in the Akonolinga Health District among pupils. Each of them was screened for the presence of peripheral blood parasites stages using Giemsa-stained thick and thin blood films. Socio-demographic information was documented using a questionnaire forms. A total of 416 pupils aged 4-15 years (average: 9.17 ± 0.27) were recruited. The overall prevalence was 4.32% and 37.26% for M. perstans and P. falciparum respectively, and prevalence of co-infection was 1.92%. Mean parasite density was 508.7±310.3 (min: 430 - max: 1300) µF/ml for M. perstans and 5240.38±2037.42 (min: 857 – max: 10400) T/μl for P. falciparum. Risks of single infections (aOR = 0.46, P = 0.0264 for M. perstans and aOR = 0.64, P = 0.0432 for P. falciparum) and co-infection (aOR = 0.10, P = 0.0371) were lower for pupils living in urban area than those living in rural area. Parasitemia of both parasite species were similar in single and co-infection situations (P> 0.05). The interaction between these parasites could involve another mechanism than a competition for blood resources. This study outlined that M. perstans and P. falciparum are co-endemic in the Akonolinga health District. In order to guarantee future success in control and eradication of malaria, a bigger attention should be given to M. perstans or other filarial where it is co-endemic with P. falciparum. VL - 7 IS - 1 ER -
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