Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle

Janet Ogochukwu Nzoputam; Ezeuchu Favour Udochukwu; Emmanuel Amabebe

doi:doi:10.11648/j.ajbls.20190701.12

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Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle

Janet Ogochukwu Nzoputam, Ezeuchu Favour Udochukwu, Emmanuel Amabebe

Published in American Journal of Biomedical and Life Sciences (Volume 7, Issue 1)

Received: 28 December 2018 Accepted: 23 January 2019 Published: 15 February 2019

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Abstract

Introduction: Electrolyte-dependent water retention associated with hormonal changes during the menstrual cycle may alter the normal reference intervals of plasma electrolytes with important effects on central nervous system, cardiovascular and renal functions. Hence, we sought to determine and compare plasma electrolytes (sodium, potassium, bicarbonate, chloride and urea) concentrations and thirst perception during different phases of the menstrual cycle. Methods: Blood samples obtained from the anti-cubital veins of 40 healthy females (18 – 25 years, 27 - 33 days menstrual cycle) on the 2nd (early follicular/menstrual, n = 10), 8th (late follicular, n = 10), 14th (ovulatory, n = 10) and 22nd (luteal, n = 10) day of the menstrual cycle were analysed for plasma electrolytes concentrations by photoelectric flame photometry. Thirst perception (TP) ratings were also obtained at the time of sample collection using the Visual Analogue Scale. Results: Plasma [Na⁺] (P = 0.003) and [Cl^-] (P = 0.02) were highest during ovulation while the late follicular and luteal phases had the least [Na⁺] and [Cl^-] respectively. Plasma [K⁺], [HCO₃^-], and [urea] did not differ significantly in relation to the phase of menstrual cycle. In addition, TP increased in a phase-dependent non-significant manner until after ovulation. Conclusion: Plasma concentrations of sodium and chloride are increased during ovulation. This may be attributed to oestrogen-related salt retention, whereas the lower sodium and chloride concentrations observed in the luteal phase (compared to ovulation especially) could be due to the natriuretic action of progesterone.

Published in	American Journal of Biomedical and Life Sciences (Volume 7, Issue 1)
DOI	10.11648/j.ajbls.20190701.12
Page(s)	6-9
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Menstrual Cycle, Plasma Electrolytes, Sodium, Chloride, Thirst

References

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APA Style

Janet Ogochukwu Nzoputam, Ezeuchu Favour Udochukwu, Emmanuel Amabebe. (2019). Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle. American Journal of Biomedical and Life Sciences, 7(1), 6-9. https://doi.org/10.11648/j.ajbls.20190701.12

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ACS Style

Janet Ogochukwu Nzoputam; Ezeuchu Favour Udochukwu; Emmanuel Amabebe. Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle. Am. J. Biomed. Life Sci. 2019, 7(1), 6-9. doi: 10.11648/j.ajbls.20190701.12

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AMA Style

Janet Ogochukwu Nzoputam, Ezeuchu Favour Udochukwu, Emmanuel Amabebe. Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle. Am J Biomed Life Sci. 2019;7(1):6-9. doi: 10.11648/j.ajbls.20190701.12

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@article{10.11648/j.ajbls.20190701.12,
  author = {Janet Ogochukwu Nzoputam and Ezeuchu Favour Udochukwu and Emmanuel Amabebe},
  title = {Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {7},
  number = {1},
  pages = {6-9},
  doi = {10.11648/j.ajbls.20190701.12},
  url = {https://doi.org/10.11648/j.ajbls.20190701.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20190701.12},
  abstract = {Introduction: Electrolyte-dependent water retention associated with hormonal changes during the menstrual cycle may alter the normal reference intervals of plasma electrolytes with important effects on central nervous system, cardiovascular and renal functions. Hence, we sought to determine and compare plasma electrolytes (sodium, potassium, bicarbonate, chloride and urea) concentrations and thirst perception during different phases of the menstrual cycle. Methods: Blood samples obtained from the anti-cubital veins of 40 healthy females (18 – 25 years, 27 - 33 days menstrual cycle) on the 2nd (early follicular/menstrual, n = 10), 8th (late follicular, n = 10), 14th (ovulatory, n = 10) and 22nd (luteal, n = 10) day of the menstrual cycle were analysed for plasma electrolytes concentrations by photoelectric flame photometry. Thirst perception (TP) ratings were also obtained at the time of sample collection using the Visual Analogue Scale. Results: Plasma [Na+] (P = 0.003) and [Cl-] (P = 0.02) were highest during ovulation while the late follicular and luteal phases had the least [Na+] and [Cl-] respectively. Plasma [K+], [HCO3-], and [urea] did not differ significantly in relation to the phase of menstrual cycle. In addition, TP increased in a phase-dependent non-significant manner until after ovulation. Conclusion: Plasma concentrations of sodium and chloride are increased during ovulation. This may be attributed to oestrogen-related salt retention, whereas the lower sodium and chloride concentrations observed in the luteal phase (compared to ovulation especially) could be due to the natriuretic action of progesterone.},
 year = {2019}
}

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TY  - JOUR
T1  - Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle
AU  - Janet Ogochukwu Nzoputam
AU  - Ezeuchu Favour Udochukwu
AU  - Emmanuel Amabebe
Y1  - 2019/02/15
PY  - 2019
N1  - https://doi.org/10.11648/j.ajbls.20190701.12
DO  - 10.11648/j.ajbls.20190701.12
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 6
EP  - 9
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20190701.12
AB  - Introduction: Electrolyte-dependent water retention associated with hormonal changes during the menstrual cycle may alter the normal reference intervals of plasma electrolytes with important effects on central nervous system, cardiovascular and renal functions. Hence, we sought to determine and compare plasma electrolytes (sodium, potassium, bicarbonate, chloride and urea) concentrations and thirst perception during different phases of the menstrual cycle. Methods: Blood samples obtained from the anti-cubital veins of 40 healthy females (18 – 25 years, 27 - 33 days menstrual cycle) on the 2nd (early follicular/menstrual, n = 10), 8th (late follicular, n = 10), 14th (ovulatory, n = 10) and 22nd (luteal, n = 10) day of the menstrual cycle were analysed for plasma electrolytes concentrations by photoelectric flame photometry. Thirst perception (TP) ratings were also obtained at the time of sample collection using the Visual Analogue Scale. Results: Plasma [Na+] (P = 0.003) and [Cl-] (P = 0.02) were highest during ovulation while the late follicular and luteal phases had the least [Na+] and [Cl-] respectively. Plasma [K+], [HCO3-], and [urea] did not differ significantly in relation to the phase of menstrual cycle. In addition, TP increased in a phase-dependent non-significant manner until after ovulation. Conclusion: Plasma concentrations of sodium and chloride are increased during ovulation. This may be attributed to oestrogen-related salt retention, whereas the lower sodium and chloride concentrations observed in the luteal phase (compared to ovulation especially) could be due to the natriuretic action of progesterone.
VL  - 7
IS  - 1
ER  -

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Author Information

Janet Ogochukwu Nzoputam

Department of Physiology, University of Benin, Benin City, Nigeria
Ezeuchu Favour Udochukwu

Department of Physiology, University of Benin, Benin City, Nigeria
Emmanuel Amabebe

Academic Unit of Reproductive and Developmental Medicine, University of Sheffield, Sheffield, UK

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Janet Ogochukwu Nzoputam, Ezeuchu Favour Udochukwu, Emmanuel Amabebe. (2019). Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle. American Journal of Biomedical and Life Sciences, 7(1), 6-9. https://doi.org/10.11648/j.ajbls.20190701.12

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ACS Style

Janet Ogochukwu Nzoputam; Ezeuchu Favour Udochukwu; Emmanuel Amabebe. Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle. Am. J. Biomed. Life Sci. 2019, 7(1), 6-9. doi: 10.11648/j.ajbls.20190701.12

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AMA Style

Janet Ogochukwu Nzoputam, Ezeuchu Favour Udochukwu, Emmanuel Amabebe. Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle. Am J Biomed Life Sci. 2019;7(1):6-9. doi: 10.11648/j.ajbls.20190701.12

Copy | Download

@article{10.11648/j.ajbls.20190701.12,
  author = {Janet Ogochukwu Nzoputam and Ezeuchu Favour Udochukwu and Emmanuel Amabebe},
  title = {Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {7},
  number = {1},
  pages = {6-9},
  doi = {10.11648/j.ajbls.20190701.12},
  url = {https://doi.org/10.11648/j.ajbls.20190701.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20190701.12},
  abstract = {Introduction: Electrolyte-dependent water retention associated with hormonal changes during the menstrual cycle may alter the normal reference intervals of plasma electrolytes with important effects on central nervous system, cardiovascular and renal functions. Hence, we sought to determine and compare plasma electrolytes (sodium, potassium, bicarbonate, chloride and urea) concentrations and thirst perception during different phases of the menstrual cycle. Methods: Blood samples obtained from the anti-cubital veins of 40 healthy females (18 – 25 years, 27 - 33 days menstrual cycle) on the 2nd (early follicular/menstrual, n = 10), 8th (late follicular, n = 10), 14th (ovulatory, n = 10) and 22nd (luteal, n = 10) day of the menstrual cycle were analysed for plasma electrolytes concentrations by photoelectric flame photometry. Thirst perception (TP) ratings were also obtained at the time of sample collection using the Visual Analogue Scale. Results: Plasma [Na+] (P = 0.003) and [Cl-] (P = 0.02) were highest during ovulation while the late follicular and luteal phases had the least [Na+] and [Cl-] respectively. Plasma [K+], [HCO3-], and [urea] did not differ significantly in relation to the phase of menstrual cycle. In addition, TP increased in a phase-dependent non-significant manner until after ovulation. Conclusion: Plasma concentrations of sodium and chloride are increased during ovulation. This may be attributed to oestrogen-related salt retention, whereas the lower sodium and chloride concentrations observed in the luteal phase (compared to ovulation especially) could be due to the natriuretic action of progesterone.},
 year = {2019}
}

Copy | Download

TY  - JOUR
T1  - Variations in Plasma Electrolytes and Thirst Perception During the Menstrual Cycle
AU  - Janet Ogochukwu Nzoputam
AU  - Ezeuchu Favour Udochukwu
AU  - Emmanuel Amabebe
Y1  - 2019/02/15
PY  - 2019
N1  - https://doi.org/10.11648/j.ajbls.20190701.12
DO  - 10.11648/j.ajbls.20190701.12
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 6
EP  - 9
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20190701.12
AB  - Introduction: Electrolyte-dependent water retention associated with hormonal changes during the menstrual cycle may alter the normal reference intervals of plasma electrolytes with important effects on central nervous system, cardiovascular and renal functions. Hence, we sought to determine and compare plasma electrolytes (sodium, potassium, bicarbonate, chloride and urea) concentrations and thirst perception during different phases of the menstrual cycle. Methods: Blood samples obtained from the anti-cubital veins of 40 healthy females (18 – 25 years, 27 - 33 days menstrual cycle) on the 2nd (early follicular/menstrual, n = 10), 8th (late follicular, n = 10), 14th (ovulatory, n = 10) and 22nd (luteal, n = 10) day of the menstrual cycle were analysed for plasma electrolytes concentrations by photoelectric flame photometry. Thirst perception (TP) ratings were also obtained at the time of sample collection using the Visual Analogue Scale. Results: Plasma [Na+] (P = 0.003) and [Cl-] (P = 0.02) were highest during ovulation while the late follicular and luteal phases had the least [Na+] and [Cl-] respectively. Plasma [K+], [HCO3-], and [urea] did not differ significantly in relation to the phase of menstrual cycle. In addition, TP increased in a phase-dependent non-significant manner until after ovulation. Conclusion: Plasma concentrations of sodium and chloride are increased during ovulation. This may be attributed to oestrogen-related salt retention, whereas the lower sodium and chloride concentrations observed in the luteal phase (compared to ovulation especially) could be due to the natriuretic action of progesterone.
VL  - 7
IS  - 1
ER  -

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